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Heart Failure With Mid-range Ejection Fraction: Every Coin Has Two Sides

This review summarizes current knowledge regarding clinical epidemiology, pathophysiology, and prognosis for patients with HFmrEF in comparison to HFrEF and HFpEF. Although recommended treatments currently focus on aggressive management of comorbidities, we summarize potentially beneficial therapies...

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Detalles Bibliográficos
Autores principales: Zhu, Kaiyuan, Ma, Teng, Su, Yang, Pan, Xin, Huang, Rongrong, Zhang, Fenglei, Yan, Chunxi, Xu, Dachun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333279/
https://www.ncbi.nlm.nih.gov/pubmed/34368245
http://dx.doi.org/10.3389/fcvm.2021.683418
Descripción
Sumario:This review summarizes current knowledge regarding clinical epidemiology, pathophysiology, and prognosis for patients with HFmrEF in comparison to HFrEF and HFpEF. Although recommended treatments currently focus on aggressive management of comorbidities, we summarize potentially beneficial therapies that can delay the process of heart failure by blocking the pathophysiology mechanism. More studies are needed to further characterize HFmrEF and identify effective management strategies that can reduce cardiovascular morbidity and mortality of patients with HFmrEF.