Heart Failure With Mid-range Ejection Fraction: Every Coin Has Two Sides

This review summarizes current knowledge regarding clinical epidemiology, pathophysiology, and prognosis for patients with HFmrEF in comparison to HFrEF and HFpEF. Although recommended treatments currently focus on aggressive management of comorbidities, we summarize potentially beneficial therapies...

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Detalles Bibliográficos
Autores principales: Zhu, Kaiyuan, Ma, Teng, Su, Yang, Pan, Xin, Huang, Rongrong, Zhang, Fenglei, Yan, Chunxi, Xu, Dachun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333279/
https://www.ncbi.nlm.nih.gov/pubmed/34368245
http://dx.doi.org/10.3389/fcvm.2021.683418
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author Zhu, Kaiyuan
Ma, Teng
Su, Yang
Pan, Xin
Huang, Rongrong
Zhang, Fenglei
Yan, Chunxi
Xu, Dachun
author_facet Zhu, Kaiyuan
Ma, Teng
Su, Yang
Pan, Xin
Huang, Rongrong
Zhang, Fenglei
Yan, Chunxi
Xu, Dachun
author_sort Zhu, Kaiyuan
collection PubMed
description This review summarizes current knowledge regarding clinical epidemiology, pathophysiology, and prognosis for patients with HFmrEF in comparison to HFrEF and HFpEF. Although recommended treatments currently focus on aggressive management of comorbidities, we summarize potentially beneficial therapies that can delay the process of heart failure by blocking the pathophysiology mechanism. More studies are needed to further characterize HFmrEF and identify effective management strategies that can reduce cardiovascular morbidity and mortality of patients with HFmrEF.
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spelling pubmed-83332792021-08-05 Heart Failure With Mid-range Ejection Fraction: Every Coin Has Two Sides Zhu, Kaiyuan Ma, Teng Su, Yang Pan, Xin Huang, Rongrong Zhang, Fenglei Yan, Chunxi Xu, Dachun Front Cardiovasc Med Cardiovascular Medicine This review summarizes current knowledge regarding clinical epidemiology, pathophysiology, and prognosis for patients with HFmrEF in comparison to HFrEF and HFpEF. Although recommended treatments currently focus on aggressive management of comorbidities, we summarize potentially beneficial therapies that can delay the process of heart failure by blocking the pathophysiology mechanism. More studies are needed to further characterize HFmrEF and identify effective management strategies that can reduce cardiovascular morbidity and mortality of patients with HFmrEF. Frontiers Media S.A. 2021-07-21 /pmc/articles/PMC8333279/ /pubmed/34368245 http://dx.doi.org/10.3389/fcvm.2021.683418 Text en Copyright © 2021 Zhu, Ma, Su, Pan, Huang, Zhang, Yan and Xu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Zhu, Kaiyuan
Ma, Teng
Su, Yang
Pan, Xin
Huang, Rongrong
Zhang, Fenglei
Yan, Chunxi
Xu, Dachun
Heart Failure With Mid-range Ejection Fraction: Every Coin Has Two Sides
title Heart Failure With Mid-range Ejection Fraction: Every Coin Has Two Sides
title_full Heart Failure With Mid-range Ejection Fraction: Every Coin Has Two Sides
title_fullStr Heart Failure With Mid-range Ejection Fraction: Every Coin Has Two Sides
title_full_unstemmed Heart Failure With Mid-range Ejection Fraction: Every Coin Has Two Sides
title_short Heart Failure With Mid-range Ejection Fraction: Every Coin Has Two Sides
title_sort heart failure with mid-range ejection fraction: every coin has two sides
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333279/
https://www.ncbi.nlm.nih.gov/pubmed/34368245
http://dx.doi.org/10.3389/fcvm.2021.683418
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