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Intraluminal Monitoring of Micro Vessels. A Surgical Feasibility Study

Objective: Monitoring of vessel perfusion is of high clinical importance in vascular anastomosis of free flaps. Current sensor systems are based on different principles and show limitations in validity and accuracy. Fiber optic pressure sensors exhibit high accuracy and are small in size. The aim of...

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Autores principales: Walle, Leonard, Sudhoff, Holger, Frerichs, Onno, Todt, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333698/
https://www.ncbi.nlm.nih.gov/pubmed/34368216
http://dx.doi.org/10.3389/fsurg.2021.681797
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author Walle, Leonard
Sudhoff, Holger
Frerichs, Onno
Todt, Ingo
author_facet Walle, Leonard
Sudhoff, Holger
Frerichs, Onno
Todt, Ingo
author_sort Walle, Leonard
collection PubMed
description Objective: Monitoring of vessel perfusion is of high clinical importance in vascular anastomosis of free flaps. Current sensor systems are based on different principles and show limitations in validity and accuracy. Fiber optic pressure sensors exhibit high accuracy and are small in size. The aim of the present study was to evaluate the surgical feasibility of intraluminal pressure (ILP) measurements with a fiber optic pressure sensor in an animal model. Methods: In a microsurgical setting we sedated 10 Wistar rats with weight adapted phenobarbital, xylazine, and fentanyl. We performed a surgical approach to A. carotis communis and V. jugularis and introduced a 600 μm fiber optic pressure sensor into the vessels followed by measuring the ILP. The sensor was stabilized by the surrounding tissue, and the vessels were closed. Results: In all cases, surgical placement was uneventful. Measurement of intra-venous and intra-arterial pressure was possible and stable over the whole measurement period of an hour. Conclusion: Fiber optic pressure measurement in microvessels is possible and surgically feasible. An application to monitor the perfusion of free flaps seems possible.
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spelling pubmed-83336982021-08-05 Intraluminal Monitoring of Micro Vessels. A Surgical Feasibility Study Walle, Leonard Sudhoff, Holger Frerichs, Onno Todt, Ingo Front Surg Surgery Objective: Monitoring of vessel perfusion is of high clinical importance in vascular anastomosis of free flaps. Current sensor systems are based on different principles and show limitations in validity and accuracy. Fiber optic pressure sensors exhibit high accuracy and are small in size. The aim of the present study was to evaluate the surgical feasibility of intraluminal pressure (ILP) measurements with a fiber optic pressure sensor in an animal model. Methods: In a microsurgical setting we sedated 10 Wistar rats with weight adapted phenobarbital, xylazine, and fentanyl. We performed a surgical approach to A. carotis communis and V. jugularis and introduced a 600 μm fiber optic pressure sensor into the vessels followed by measuring the ILP. The sensor was stabilized by the surrounding tissue, and the vessels were closed. Results: In all cases, surgical placement was uneventful. Measurement of intra-venous and intra-arterial pressure was possible and stable over the whole measurement period of an hour. Conclusion: Fiber optic pressure measurement in microvessels is possible and surgically feasible. An application to monitor the perfusion of free flaps seems possible. Frontiers Media S.A. 2021-07-21 /pmc/articles/PMC8333698/ /pubmed/34368216 http://dx.doi.org/10.3389/fsurg.2021.681797 Text en Copyright © 2021 Walle, Sudhoff, Frerichs and Todt. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Walle, Leonard
Sudhoff, Holger
Frerichs, Onno
Todt, Ingo
Intraluminal Monitoring of Micro Vessels. A Surgical Feasibility Study
title Intraluminal Monitoring of Micro Vessels. A Surgical Feasibility Study
title_full Intraluminal Monitoring of Micro Vessels. A Surgical Feasibility Study
title_fullStr Intraluminal Monitoring of Micro Vessels. A Surgical Feasibility Study
title_full_unstemmed Intraluminal Monitoring of Micro Vessels. A Surgical Feasibility Study
title_short Intraluminal Monitoring of Micro Vessels. A Surgical Feasibility Study
title_sort intraluminal monitoring of micro vessels. a surgical feasibility study
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333698/
https://www.ncbi.nlm.nih.gov/pubmed/34368216
http://dx.doi.org/10.3389/fsurg.2021.681797
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