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METTL3/YTHDF2 m6A axis accelerates colorectal carcinogenesis through epigenetically suppressing YPEL5

N6‐methyladenosine (m6A) has emerged as the most prevalent post‐transcriptional modification on mRNA that contributes prominently to tumorigenesis. However, the specific function of m6A methyltransferase methyltransferase‐like 3 (METTL3) in colorectal cancer (CRC) remains elusive. Herein, we explore...

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Detalles Bibliográficos
Autores principales: Zhou, Dan, Tang, Weiwei, Xu, Yidan, Xu, Yajie, Xu, Binbin, Fu, Shanshan, Wang, Yanting, Chen, Fangfang, Chen, Yongxiong, Han, Yinshu, Wang, Gueyhorng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333777/
https://www.ncbi.nlm.nih.gov/pubmed/33411363
http://dx.doi.org/10.1002/1878-0261.12898