cAMP Response Element-Binding Protein- and Phosphorylation-Dependent Regulation of Tyrosine Hydroxylase by PAK4: Implications for Dopamine Replacement Therapy

Parkinson’s disease (PD) is characterized by a progressive loss of dopamine-producing neurons in the midbrain, which results in decreased dopamine levels accompanied by movement symptoms. Oral administration of l-3,4-dihydroxyphenylalanine (L-dopa), the precursor of dopamine, provides initial sympto...

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Detalles Bibliográficos
Autores principales: Won, So-Yoon, You, Soon-Tae, Choi, Seung-Won, McLean, Catriona, Shin, Eun-Young, Kim, Eung-Gook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334344/
https://www.ncbi.nlm.nih.gov/pubmed/34238765
http://dx.doi.org/10.14348/molcells.2021.2250

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