A Novel Probable Pathogenic PSEN2 Mutation p.Phe369Ser Associated With Early-Onset Alzheimer's Disease in a Chinese Han Family: A Case Report

The pathogenesis of Alzheimer's disease is complex, and early-onset Alzheimer's disease (EOAD) is mostly influenced by genetic factors. Presenilin-1, presenilin-2 (PSEN2), and amyloid precursor protein are currently known as the three main causative genes for autosomal dominant EOAD, with...

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Detalles Bibliográficos
Autores principales: Wan, Ke, Ma, Zhen-Juan, Zhou, Xia, Zhang, Yi-Mei, Yu, Xian-Feng, You, Meng-Zhe, Huang, Chao-Juan, Zhang, Wei, Sun, Zhong-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334358/
https://www.ncbi.nlm.nih.gov/pubmed/34366829
http://dx.doi.org/10.3389/fnagi.2021.710075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334358/
https://www.ncbi.nlm.nih.gov/pubmed/34366829
http://dx.doi.org/10.3389/fnagi.2021.710075

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