Cargando…

Valproic Acid Ameliorates Locomotor Function in the Rat Model of Contusion via Alteration of Mst1, Bcl-2, and Nrf2 Gene Expression

BACKGROUND: In animal models of inflammatory diseases, Mst1 facilitates the programmed cell death as a novel pro-apoptotic kinase. This research aimed to determine the expression level of Mst1 gene in a rat model of SCI treated with VPA. METHODS: Severe rat model contusion was used for evaluation of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mardi, Ali, Biglari, Alireza, Nejatbakhsh, Reza, Abdanipour, Alireza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Pasteur Institute of Iran 2021
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334391/ https://www.ncbi.nlm.nih.gov/pubmed/34217161 http://dx.doi.org/10.52547/ibj.25.4.303

Ejemplares similares

Di-(2-ethylhexyl) Phthalate-Induced Hippocampus-Derived Neural Stem Cells Proliferation
por: Abdanipour, Alireza, et al.
Publicado: (2017)

Intraspinal transplantation of motoneuron-like cell combined with delivery of polymer-based glial cell line-derived neurotrophic factor for repair of spinal cord contusion injury
por: Abdanipour, Alireza, et al.
Publicado: (2014)

Indirect Co-Culture of Testicular Cells with Bone Marrow Mesenchymal Stem Cells Leads to Male Germ Cell-Specific Gene Expressions
por: Ghorbanlou, Mehrdad, et al.
Publicado: (2019)

Effect of Ghrelin on Caspase 3 and Bcl2 Gene Expression in H2O2 Treated Rat’s Bone Marrow Stromal Cells
por: Abdanipour, Alireza, et al.
Publicado: (2018)

Neuroprotective effect of L-deprenyl on the expression level of the Mst1 gene and inhibition of apoptosis in rat-model spinal cord injury
por: Abdanipour, Alireza, et al.
Publicado: (2022)

Mst1 inhibits autophagy by promoting Beclin1-Bcl-2 interaction
por: Maejima, Yasuhiro, et al.
Publicado: (2013)

Mst1 and Mst2 kinases: regulations and diseases
por: Qin, Funiu, et al.
Publicado: (2013)

Effect of Inactivation of Mst1 and Mst2 in the Mouse Adrenal Cortex
por: Abou Nader, Nour, et al.
Publicado: (2022)

Locomotor recovery following contusive spinal cord injury does not require oligodendrocyte remyelination
por: Duncan, Greg J., et al.
Publicado: (2018)

Functional Role of Mst1/Mst2 in Embryonic Stem Cell Differentiation
por: Li, Peng, et al.
Publicado: (2013)

Mst1 and Mst2 Are Essential Regulators of Trophoblast Differentiation and Placenta Morphogenesis
por: Du, Xingrong, et al.
Publicado: (2014)

Role of the Polyol Pathway in Locomotor Recovery and Wallerian Degeneration after Spinal Cord Contusion Injury
por: Zeman, Richard J., et al.
Publicado: (2021)

The effect of cryoprecipitate on prevention of intra cerebral hemorrhage and brain contusion expansion in traumatic patients
por: Saeidiborojeni, Hamidreza, et al.
Publicado: (2022)

Macrophage achieves self-protection against oxidative stress-induced ageing through the Mst-Nrf2 axis
por: Wang, Ping, et al.
Publicado: (2019)

The kinases Mst1 and Mst2 positively regulate phagocyte ROS induction and bactericidal activity
por: Geng, Jing, et al.
Publicado: (2015)

Pulmonary contusion during the COVID-19 pandemic: challenges in diagnosis and treatment
por: Wang, Yongyong, et al.
Publicado: (2020)

Valproic Acid Sensitizes Hepatocellular Carcinoma Cells to Proton Therapy by Suppressing NRF2 Activation
por: Yu, Jeong Il, et al.
Publicado: (2017)

The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes
por: Mou, Fan, et al.
Publicado: (2012)

Synaptosomal-associated protein 25 may be an intervention target for improving sensory and locomotor functions after spinal cord contusion
por: Zhong, Zhan-qiong, et al.
Publicado: (2017)

Limited changes in locomotor recovery and unaffected white matter sparing after spinal cord contusion at different times of day
por: Slomnicki, Lukasz P., et al.
Publicado: (2021)

Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2
por: Loforese, Giulio, et al.
Publicado: (2016)

FGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1/2-dependent apoptosis
por: Turunen, S. Pauliina, et al.
Publicado: (2019)

Survey of MST Studies
por: Barbalat, O
Publicado: (1974)

Ghrelin Upregulates Hoxb4 Gene Expression in Rat Bone Marrow Stromal Cells
por: Abdanipour, Alireza, et al.
Publicado: (2018)

Lung contusion
por: Arjun, Padmanabhan, et al.
Publicado: (2018)

Improvement of Contused Spinal Cord in Rats by Cholinergic-like Neuron Therapy
por: Naghdi, Majid, et al.
Publicado: (2013)

Ibrutinib reduces neutrophil infiltration, preserves neural tissue and enhances locomotor recovery in mouse contusion model of spinal cord injury
por: Torabi, Somayyeh, et al.
Publicado: (2021)

BCL-2 AND IAP Proteins As Potential Drug Targets
por: Fesik, Stephen W.
Publicado: (2001)

Publisher Correction: Valproic Acid Sensitizes Hepatocellular Carcinoma Cells to Proton Therapy by Suppressing NRF2 Activation
por: Yu, Jeong Il, et al.
Publicado: (2018)

The effectiveness of caffeinated chewing gum in ameliorating cognitive functions affected by sleep deprivation
por: Moradi, AliReza, et al.
Publicado: (2022)

Comparison of human adipose-derived stem cells and chondroitinase ABC transplantation on locomotor recovery in the contusion model of spinal cord injury in rats
por: Sarveazad, Arash, et al.
Publicado: (2014)

Protease-Activated Receptor-1 Supports Locomotor Recovery by Biased Agonist Activated Protein C after Contusive Spinal Cord Injury
por: Whetstone, William D., et al.
Publicado: (2017)

Improved locomotor recovery after contusive spinal cord injury in Bmal1(−/−) mice is associated with protection of the blood spinal cord barrier
por: Slomnicki, Lukasz P., et al.
Publicado: (2020)

Hypoxia-inducible factor prolyl hydroxylase domain (PHD) inhibition after contusive spinal cord injury does not improve locomotor recovery
por: Wei, George Z., et al.
Publicado: (2021)

Locomotor Exercise Enhances Supraspinal Control of Lower-Urinary-Tract Activity to Improve Micturition Function after Contusive Spinal-Cord Injury
por: Deng, Lingxiao, et al.
Publicado: (2022)

B Cell Precursors in Senescent Mice Exhibit Decreased Mitotic Recruitment, Increased Apoptosis, and Altered Expression of Bcl-2 Family Members
por: Riley, Richard L., et al.
Publicado: (2001)

Tea polyphenols alleviate hydrogen peroxide-induced oxidative stress damage through the Mst/Nrf2 axis and the Keap1/Nrf2/HO-1 pathway in murine RAW264.7 cells
por: Li, Qian, et al.
Publicado: (2021)

Expression of bcl-2 and p53 in bovine cutaneous fibropapillomas
por: Bocaneti, Florentina, et al.
Publicado: (2015)

Zinc attenuates ferroptosis and promotes functional recovery in contusion spinal cord injury by activating Nrf2/GPX4 defense pathway
por: Ge, Ming‐hao, et al.
Publicado: (2021)

MST kinases in development and disease
por: Thompson, Barry J., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_v4dn6gocrqqteju88kq9frsnds