Cargando…

Woodchuck Hepatitis Virus Post-Transcriptional Regulation Element (WPRE) Promotes Anti-CD19 BiTE Expression in Expi293 Cells

BACKGROUND: Bispecific antibodies represent an important class of mAbs, with great therapeutic potentials due to their ability to target simultaneously two distinct epitopes. The generation of functional bispecific antibodies with the highest possible yields is particularly critical for the producti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moazzami, Reza, Mirzahoseini, Hasan, Nematollahi, Leila, Barkhordari, Farzaneh, Raigani, Mozhgan, Hajari Taheri, Fatemeh, Mahboudi, Fereidoun, Davami, Fatemeh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Pasteur Institute of Iran 2021
Materias:	Full Length
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334396/ https://www.ncbi.nlm.nih.gov/pubmed/34217158 http://dx.doi.org/10.52547/ibj.25.4.275

Ejemplares similares

Optimization of EnBase Fed-Batch Cultivation to Improve Soluble Fraction Ratio of α-Luffin Ribosome Inactivating Protein
por: Barkhordari, Farzaneh, et al.
Publicado: (2018)

Effects of Peptone Supplementation in Different Culture Media on Growth, Metabolic Pathway and Productivity of CHO DG44 Cells; a New Insight into Amino Acid Profiles
por: Davami, Fatemeh, et al.
Publicado: (2015)

Production of an Antibody Fragment (scFv) Targeting PcrV Protein of Pseudomonas aeruginosa in Fed-Batch Cultivation Mode
por: Karam, Saba, et al.
Publicado: (2021)

Scale up and pharmacokinetic study of a novel mutated chimeric tissue plasminogen activator (mt-PA) in rats
por: Raigani, Mozhgan, et al.
Publicado: (2017)

Effect of Peptone Feeding on Transient Gene Expression Process in CHO DG44
por: Davami, Fatemeh, et al.
Publicado: (2014)

Proteomics Profiling of Chimeric-Truncated Tissue Plasminogen activator Producing- Chinese Hamster Ovary Cells Cultivated in a Chemically Defined Medium Supplemented with Protein Hydrolysates
por: Azarian, Bahareh, et al.
Publicado: (2017)

MALDI-MS: a Rapid and Reliable Method for Drug-to-Antibody Ratio Determination of Antibody-Drug Conjugates
por: Abedi, Mehri, et al.
Publicado: (2019)

Evaluating the efficiency of CHEF and CMV promoter with IRES and Furin/2A linker sequences for monoclonal antibody expression in CHO cells
por: Ebadat, Saeedeh, et al.
Publicado: (2017)

Exploring Parametric and Mechanistic Differences between Expi293F(TM) and ExpiCHO-S(TM) Cells for Transient Antibody Production Optimization
por: Zhou, Jing, et al.
Publicado: (2023)

Monoclonal antibodies expression improvement in CHO cells by PiggyBac transposition regarding vectors ratios and design
por: Ahmadi, Samira, et al.
Publicado: (2017)

Efficient and inexpensive transient expression of multispecific multivalent antibodies in Expi293 cells
por: Fang, Xiaotian T., et al.
Publicado: (2017)

Antibody Light Chains: Key to Increased Monoclonal Antibody Yields in Expi293 Cells?
por: Gong, Siqi, et al.
Publicado: (2022)

A versatile genomic transgenesis platform with enhanced λ integrase for human Expi293F cells
por: Siddiqui, Asim Azhar, et al.
Publicado: (2023)

Periplasmic Expression of a Novel Human Bone Morphogenetic Protein-7 Mutant in Escherichia coli
por: Nematollahi, Leila, et al.
Publicado: (2012)

Characterization of a novel mCH3 conjugated anti-PcrV scFv molecule
por: Komijani, Samira, et al.
Publicado: (2021)

Quantitative Proteomic Analysis of Cellular Responses to a Designed Amino Acid Feed in a Monoclonal Antibody Producing Chinese Hamster Ovary Cell Line
por: Torkashvand, Fatemeh, et al.
Publicado: (2018)

Construction of a Mammalian IRES-based Expression Vector to Amplify a Bispecific Antibody; Blinatumomab
por: Naddafi, Fatemeh, et al.
Publicado: (2019)

Designed Amino Acid Feed in Improvement of Production and Quality Targets of a Therapeutic Monoclonal Antibody
por: Torkashvand, Fatemeh, et al.
Publicado: (2015)

The Epigenetic Regulation of Blinatumomab Gene Expression: Tumor Cell-dependent T cell Response against Lymphoma Cells and Cytotoxic Activity
por: Naddafi, Fatemeh, et al.
Publicado: (2019)

Evaluating the expression profile and stability of different UCOE containing vector combinations in mAb-producing CHO cells
por: Nematpour, Fatemeh, et al.
Publicado: (2017)

Human Tissue Plasminogen Activator Expression in Escherichia coli using Cytoplasmic and Periplasmic Cumulative Power
por: Majidzadeh-A, Keivan, et al.
Publicado: (2010)

Engineered Jurkat Cells for Targeting Prostate-Specific Membrane Antigen on Prostate Cancer Cells by Nanobody-Based Chimeric Antigen Receptor
por: Hassani, Mahmoud, et al.
Publicado: (2020)

Molecular characterization of woodchuck IFI16 and AIM2 and their expression in woodchucks infected with woodchuck hepatitis virus (WHV)
por: Yan, Qi, et al.
Publicado: (2016)

Expression of a Novel Chimeric Truncated t-PA in CHO Cells Based on in Silico Experiments
por: Davami, Fatemeh, et al.
Publicado: (2010)

Improved microRNA suppression by WPRE-linked tough decoy microRNA sponges
por: Hollensen, Anne Kruse, et al.
Publicado: (2017)

Enzyme‐altered Liver Cell Foci in Woodchucks Infected with Woodchuck Hepatitis Virus
por: Abe, Kenji, et al.
Publicado: (1988)

Efficient site-specific integration in CHO-K1 cells using CRISPR/Cas9-modified donors
por: Kheirandish, Mohammad Hassan, et al.
Publicado: (2023)

Innate and adaptive immunity associated with resolution of acute woodchuck hepatitis virus infection in adult woodchucks
por: Suresh, Manasa, et al.
Publicado: (2019)

Combination Treatment with the Vimentin-Targeting Antibody hzVSF and Tenofovir Suppresses Woodchuck Hepatitis Virus Infection in Woodchucks
por: Korolowicz, Kyle E., et al.
Publicado: (2021)

ExpI and PhzI Are Descendants of the Long Lost Cognate Signal Synthase for SdiA
por: Sabag-Daigle, Anice, et al.
Publicado: (2012)

Expression, purification and characterization of SARS-CoV-2 spike RBD in ExpiCHO cells
por: De March, Matteo, et al.
Publicado: (2022)

A Survey of the Common Mutations and IVS8-Tn Polymorphism of Cystic Fibrosis Transmembrane Conductance Regulator Gene in Infertile Men with Nonobstructive Azoospermia and CBAVD in Iranian Population
por: Asadi, Fatemeh, et al.
Publicado: (2019)

Comparison of the expression and toxicity of AAV2/9 carrying the human A53T α-synuclein gene in presence or absence of WPRE
por: Sun, Xiuping, et al.
Publicado: (2021)

Immune Effects of Cryoablation in Woodchuck Hepatocellular Carcinoma
por: Mauda-Havakuk, Michal, et al.
Publicado: (2023)

Efficacy of an Inhibitor of Hepatitis B Virus Expression in Combination With Entecavir and Interferon‐α in Woodchucks Chronically Infected With Woodchuck Hepatitis Virus
por: Menne, Stephan, et al.
Publicado: (2020)

The Lcn2-engineered HEK-293 cells show senescence under stressful condition
por: Bahmani, Bahareh, et al.
Publicado: (2015)

Development of polyclonal heavy chain antibodies targeting programmed death ligand-1
por: Oghalaie, Akbar, et al.
Publicado: (2023)

Improvement of Certolizumab Fab′ properties by PASylation technology
por: Mazaheri, Somayeh, et al.
Publicado: (2020)

AIC649 Induces a Bi-Phasic Treatment Response in the Woodchuck Model of Chronic Hepatitis B
por: Paulsen, Daniela, et al.
Publicado: (2015)

Therapeutic Vaccination in Chronic Hepatitis B: Preclinical Studies in the Woodchuck
por: Kosinska, Anna D., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_lhnb8qddeg87b3rqs81kpn9pfl