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Increased Proportion of CD226(+) B Cells Is Associated With the Disease Activity and Prognosis of Systemic Lupus Erythematosus

BACKGROUND: CD226, an activating receptor expressed on the surface of natural killer (NK) cells and T cells, is also seen on B cells and CD226 polymorphism is associated with systemic lupus erythematosus (SLE). Because the specific roles of CD226(+) B cells in SLE are still unknown, we investigated...

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Detalles Bibliográficos
Autores principales: Nakano, Miki, Ayano, Masahiro, Kushimoto, Kazuo, Kawano, Shotaro, Higashioka, Kazuhiko, Inokuchi, Shoichiro, Mitoma, Hiroki, Kimoto, Yasutaka, Akahoshi, Mitsuteru, Ono, Nobuyuki, Arinobu, Yojiro, Akashi, Koichi, Horiuchi, Takahiko, Niiro, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334729/
https://www.ncbi.nlm.nih.gov/pubmed/34367178
http://dx.doi.org/10.3389/fimmu.2021.713225