Reactivating a positive feedback loop VTA-BLA-NAc circuit associated with positive experience ameliorates the attenuated reward sensitivity induced by chronic stress

Both genetic predisposition and life events, particularly life stress, are thought to increase the risk for depression. Reward sensitivity appears to be attenuated in major depressive disorder (MDD), suggesting deficits in reward processing in these patients. We identified the VTA-BLA-NAc circuit as...

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Detalles Bibliográficos
Autores principales: Sun, Linshan, You, Jingjing, Sun, Fengjiao, Cui, Minghu, Wang, Jiangong, Wang, Wentao, Wang, Dan, Liu, Dunjiang, Xu, Zhicheng, Qiu, Changyun, Liu, Bin, Yan, Haijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334743/
https://www.ncbi.nlm.nih.gov/pubmed/34381852
http://dx.doi.org/10.1016/j.ynstr.2021.100370

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