Changes in N6-Methyladenosine Modification Modulate Diabetic Cardiomyopathy by Reducing Myocardial Fibrosis and Myocyte Hypertrophy

In this study, we aimed to systematically profile global RNA N6-methyladenosine (m(6)A) modification patterns in a mouse model of diabetic cardiomyopathy (DCM). Patterns of m(6)A in DCM and normal hearts were analyzed via m(6)A-specific methylated RNA immunoprecipitation followed by high-throughput...

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Detalles Bibliográficos
Autores principales: Ju, Wenhao, Liu, Kai, Ouyang, Shengrong, Liu, Zhuo, He, Feng, Wu, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334868/
https://www.ncbi.nlm.nih.gov/pubmed/34368154
http://dx.doi.org/10.3389/fcell.2021.702579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8334868/
https://www.ncbi.nlm.nih.gov/pubmed/34368154
http://dx.doi.org/10.3389/fcell.2021.702579

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