Hyperbaric Oxygen Therapy Represses the Warburg Effect and Epithelial–Mesenchymal Transition in Hypoxic NSCLC Cells via the HIF-1α/PFKP Axis

BACKGROUND: Tumor cells initiate hypoxia-induced mechanisms to fuel cell proliferation, invasion, and metastasis, largely mediated by low O(2)-responsive Hypoxia-Inducible Factor 1 Alpha (HIF-1α). Therefore, hyperbaric oxygen therapy (HBO) is now being studied in cancer patients, but its impact upon...

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Detalles Bibliográficos
Autores principales: Zhang, Linling, Ke, Jingjing, Min, Shengping, Wu, Nan, Liu, Fei, Qu, Zhen, Li, Wei, Wang, Hongtao, Qian, Zhongqing, Wang, Xiaojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335162/
https://www.ncbi.nlm.nih.gov/pubmed/34367973
http://dx.doi.org/10.3389/fonc.2021.691762

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