Kakonein restores diabetes‐induced endothelial junction dysfunction via promoting autophagy‐mediated NLRP3 inflammasome degradation

In diabetes‐induced complications, inflammatory‐mediated endothelial dysfunction is the core of disease progression. Evidence shows that kakonein, an isoflavone common in Pueraria, can effectively treat diabetes and its complications. Therefore, we explored whether kakonein protects cardiovascular e...

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Detalles Bibliográficos
Autores principales: Lian, Dawei, Liu, Jiaying, Han, Ruifang, Jin, Jiaqi, Zhu, Li, Zhang, Yanhong, Huang, Yi, Wang, Xiao, Xian, Shaoxiang, Chen, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335672/
https://www.ncbi.nlm.nih.gov/pubmed/34180143
http://dx.doi.org/10.1111/jcmm.16747

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