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NAADP‐induced intracellular calcium ion is mediated by the TPCs (two‐pore channels) in hypoxia‐induced pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a form of obstructive vascular disease. Chronic hypoxic exposure leads to excessive proliferation of pulmonary arterial smooth muscle cells and pulmonary arterial endothelial cells. This condition can potentially be aggravated by [Ca(2+)] (i) mobilization. In...

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Detalles Bibliográficos
Autores principales: Hu, Wen, Zhao, Fei, Chen, Ling, Ni, Jiamin, Jiang, Yongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335677/
https://www.ncbi.nlm.nih.gov/pubmed/34263977
http://dx.doi.org/10.1111/jcmm.16783