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Pharmacokinetic and pharmacodynamic studies of CD19 CAR T cell in human leukaemic xenograft models with dual‐modality imaging

In recent years, chimeric antigen receptor T (CAR T)‐cell therapy has shown great potential in treating haematologic disease, but no breakthrough has been achieved in solid tumours. In order to clarify the antitumour mechanism of CAR T cell in solid tumours, the pharmacokinetic (PK) and pharmacodyna...

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Detalles Bibliográficos
Autores principales: Wu, Qiong, Wang, Yan, Wang, Xinyu, Liang, Ningxia, Liu, Jingjing, Pan, Donghui, Xu, Yuping, Wang, Lizhen, Yan, Junjie, Wang, Guangji, Miao, Liyan, Yang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335694/
https://www.ncbi.nlm.nih.gov/pubmed/34245101
http://dx.doi.org/10.1111/jcmm.16776