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Non-acidic bifunctional benzothiazole-based thiazolidinones with antimicrobial and aldose reductase inhibitory activity as a promising therapeutic strategy for sepsis

Sepsis is a life-threatening disease that affects millions of people worldwide. Microbial infections that lead to sepsis syndrome are associated with an increased production of inflammatory molecules. Aldose reductase has recently emerged as a molecular target that is involved in various inflammator...

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Detalles Bibliográficos
Autores principales: Kousaxidis, Antonios, Kovacikova, Lucia, Nicolaou, Ioannis, Stefek, Milan, Geronikaki, Athina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335715/
https://www.ncbi.nlm.nih.gov/pubmed/34366640
http://dx.doi.org/10.1007/s00044-021-02778-7