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Non-acidic bifunctional benzothiazole-based thiazolidinones with antimicrobial and aldose reductase inhibitory activity as a promising therapeutic strategy for sepsis
Sepsis is a life-threatening disease that affects millions of people worldwide. Microbial infections that lead to sepsis syndrome are associated with an increased production of inflammatory molecules. Aldose reductase has recently emerged as a molecular target that is involved in various inflammator...
Autores principales: | Kousaxidis, Antonios, Kovacikova, Lucia, Nicolaou, Ioannis, Stefek, Milan, Geronikaki, Athina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335715/ https://www.ncbi.nlm.nih.gov/pubmed/34366640 http://dx.doi.org/10.1007/s00044-021-02778-7 |
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