Triapine Analogues and Their Copper(II) Complexes: Synthesis, Characterization, Solution Speciation, Redox Activity, Cytotoxicity, and mR2 RNR Inhibition

[Image: see text] Three new thiosemicarbazones (TSCs) HL(1)–HL(3) as triapine analogues bearing a redox-active phenolic moiety at the terminal nitrogen atom were prepared. Reactions of HL(1)–HL(3) with CuCl(2)·2H(2)O in anoxic methanol afforded three copper(II) complexes, namely, Cu(HL(1))Cl(2) (1),...

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Detalles Bibliográficos
Autores principales: Besleaga, Iuliana, Stepanenko, Iryna, Petrasheuskaya, Tatsiana V., Darvasiova, Denisa, Breza, Martin, Hammerstad, Marta, Marć, Małgorzata A., Prado-Roller, Alexander, Spengler, Gabriella, Popović-Bijelić, Ana, Enyedy, Eva A., Rapta, Peter, Shutalev, Anatoly D., Arion, Vladimir B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335727/
https://www.ncbi.nlm.nih.gov/pubmed/34279079
http://dx.doi.org/10.1021/acs.inorgchem.1c01275

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