ALOX5‐5‐HETE promotes gastric cancer growth and alleviates chemotherapy toxicity via MEK/ERK activation

BACKGROUND: Recent studies highlight the regulatory role of arachidonate lipoxygenase5 (Alox5) and its metabolite 5‐hydroxyeicosatetraenoic acid (5‐HETE) in cancer tumorigenesis and progression. In this study, we analyzed the expression, biological function and the downstream signaling of Alox5 in g...

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Detalles Bibliográficos
Autores principales: Tang, Jianjun, Zhang, Chuang, Lin, Jingjing, Duan, Peng, Long, Jian, Zhu, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335819/
https://www.ncbi.nlm.nih.gov/pubmed/34121352
http://dx.doi.org/10.1002/cam4.4066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335819/
https://www.ncbi.nlm.nih.gov/pubmed/34121352
http://dx.doi.org/10.1002/cam4.4066

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