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Erythema induratum of Bazin as an indicative manifestation of cavitary tuberculosis in an adolescent: a case report

BACKGROUND: Erythema induratum of Bazin (EIB) is a rare cutaneous manifestation of tuberculosis (TB) that frequently occurs in middle-aged women. The clinical manifestations of EIB can mimic various skin diseases, easily leading to misdiagnosis or underdiagnosis. We report a case of a 16-year-old Ch...

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Autores principales: Yang, Kun, Li, Tingying, Zhu, Xiaomei, Zou, Yun, Liu, Dongxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335867/
https://www.ncbi.nlm.nih.gov/pubmed/34344358
http://dx.doi.org/10.1186/s12879-021-06454-4
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author Yang, Kun
Li, Tingying
Zhu, Xiaomei
Zou, Yun
Liu, Dongxian
author_facet Yang, Kun
Li, Tingying
Zhu, Xiaomei
Zou, Yun
Liu, Dongxian
author_sort Yang, Kun
collection PubMed
description BACKGROUND: Erythema induratum of Bazin (EIB) is a rare cutaneous manifestation of tuberculosis (TB) that frequently occurs in middle-aged women. The clinical manifestations of EIB can mimic various skin diseases, easily leading to misdiagnosis or underdiagnosis. We report a case of a 16-year-old Chinese girl who initially presented with EIB and was subsequently diagnosed with cavitary TB. CASE PRESENTATION: The patient is a 16-year-old Chinese girl who presented with clusters of erythematous subcutaneous nodules on the posterior part of her right lower leg matching the clinical manifestations of EIB but was otherwise asymptomatic. The patient was subsequently diagnosed with cavitary TB on the basis of a positive result from a T-SPOT.TB test and the observation of cavitary lung lesions in chest computed tomography scanning. A good clinical response was observed in the patient after the initial phase of a standard 6-month antibiotic regimen. CONCLUSIONS: Adolescents infected with Mycobacterium tuberculosis frequently present atypical symptoms. Cutaneous manifestations of tuberculosis in adolescents can be considered good clinical indicators to predict the underlying disease. Strong clinical suspicion is required for a prompt diagnosis in adolescents with EIB.
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spelling pubmed-83358672021-08-04 Erythema induratum of Bazin as an indicative manifestation of cavitary tuberculosis in an adolescent: a case report Yang, Kun Li, Tingying Zhu, Xiaomei Zou, Yun Liu, Dongxian BMC Infect Dis Case Report BACKGROUND: Erythema induratum of Bazin (EIB) is a rare cutaneous manifestation of tuberculosis (TB) that frequently occurs in middle-aged women. The clinical manifestations of EIB can mimic various skin diseases, easily leading to misdiagnosis or underdiagnosis. We report a case of a 16-year-old Chinese girl who initially presented with EIB and was subsequently diagnosed with cavitary TB. CASE PRESENTATION: The patient is a 16-year-old Chinese girl who presented with clusters of erythematous subcutaneous nodules on the posterior part of her right lower leg matching the clinical manifestations of EIB but was otherwise asymptomatic. The patient was subsequently diagnosed with cavitary TB on the basis of a positive result from a T-SPOT.TB test and the observation of cavitary lung lesions in chest computed tomography scanning. A good clinical response was observed in the patient after the initial phase of a standard 6-month antibiotic regimen. CONCLUSIONS: Adolescents infected with Mycobacterium tuberculosis frequently present atypical symptoms. Cutaneous manifestations of tuberculosis in adolescents can be considered good clinical indicators to predict the underlying disease. Strong clinical suspicion is required for a prompt diagnosis in adolescents with EIB. BioMed Central 2021-08-03 /pmc/articles/PMC8335867/ /pubmed/34344358 http://dx.doi.org/10.1186/s12879-021-06454-4 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Yang, Kun
Li, Tingying
Zhu, Xiaomei
Zou, Yun
Liu, Dongxian
Erythema induratum of Bazin as an indicative manifestation of cavitary tuberculosis in an adolescent: a case report
title Erythema induratum of Bazin as an indicative manifestation of cavitary tuberculosis in an adolescent: a case report
title_full Erythema induratum of Bazin as an indicative manifestation of cavitary tuberculosis in an adolescent: a case report
title_fullStr Erythema induratum of Bazin as an indicative manifestation of cavitary tuberculosis in an adolescent: a case report
title_full_unstemmed Erythema induratum of Bazin as an indicative manifestation of cavitary tuberculosis in an adolescent: a case report
title_short Erythema induratum of Bazin as an indicative manifestation of cavitary tuberculosis in an adolescent: a case report
title_sort erythema induratum of bazin as an indicative manifestation of cavitary tuberculosis in an adolescent: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335867/
https://www.ncbi.nlm.nih.gov/pubmed/34344358
http://dx.doi.org/10.1186/s12879-021-06454-4
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