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FOXD1 promotes EMT and cell stemness of oral squamous cell carcinoma by transcriptional activation of SNAI2

BACKGROUND: Epithelial-mesenchymal transition (EMT) and cell stemness are implicated in the initiation and progression of oral squamous cell carcinoma (OSCC). Revealing the intrinsic regulatory mechanism may provide effective therapeutic targets for OSCC. RESULTS: In this study, we found that Forkhe...

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Detalles Bibliográficos
Autores principales: Chen, Yang, Liang, Weilian, Liu, Ke, Shang, Zhengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8335989/
https://www.ncbi.nlm.nih.gov/pubmed/34348789
http://dx.doi.org/10.1186/s13578-021-00671-9