A mass in the upper abdomen derived from Talaromyces marneffei infected lymphadenopathy: a case report

BACKGROUND: An upper abdominal mass without tenderness often indicates a benign or malignant tumor once liver or spleen hyperplasia has been excluded. A lymphadenopathic mass from Talaromyces marneffei infection is rare. CASE PRESENTATION: We report the case of a 29-year-old human immunodeficiency v...

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Autores principales: Chen, Xue, Jia, Lin, Wu, Yongfeng, Chang, Jing, Zhang, Tong, Ma, Yingmin, Zhang, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336084/
https://www.ncbi.nlm.nih.gov/pubmed/34348692
http://dx.doi.org/10.1186/s12879-021-06489-7
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author Chen, Xue
Jia, Lin
Wu, Yongfeng
Chang, Jing
Zhang, Tong
Ma, Yingmin
Zhang, Yulin
author_facet Chen, Xue
Jia, Lin
Wu, Yongfeng
Chang, Jing
Zhang, Tong
Ma, Yingmin
Zhang, Yulin
author_sort Chen, Xue
collection PubMed
description BACKGROUND: An upper abdominal mass without tenderness often indicates a benign or malignant tumor once liver or spleen hyperplasia has been excluded. A lymphadenopathic mass from Talaromyces marneffei infection is rare. CASE PRESENTATION: We report the case of a 29-year-old human immunodeficiency virus (HIV) infected man who presented with an upper abdominal mass and without any symptoms related with infection. Histopathology and next-generation sequencing (NGS) following biopsy of the mass confirmed T. marneffei-infected lymphadenopathy, and the patient was successfully treated with amphotericin B and itraconazole. CONCLUSIONS: This case report suggests that potential fungal infection should be considered during the diagnostic workup of a mass in clinical practice.
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spelling pubmed-83360842021-08-04 A mass in the upper abdomen derived from Talaromyces marneffei infected lymphadenopathy: a case report Chen, Xue Jia, Lin Wu, Yongfeng Chang, Jing Zhang, Tong Ma, Yingmin Zhang, Yulin BMC Infect Dis Case Report BACKGROUND: An upper abdominal mass without tenderness often indicates a benign or malignant tumor once liver or spleen hyperplasia has been excluded. A lymphadenopathic mass from Talaromyces marneffei infection is rare. CASE PRESENTATION: We report the case of a 29-year-old human immunodeficiency virus (HIV) infected man who presented with an upper abdominal mass and without any symptoms related with infection. Histopathology and next-generation sequencing (NGS) following biopsy of the mass confirmed T. marneffei-infected lymphadenopathy, and the patient was successfully treated with amphotericin B and itraconazole. CONCLUSIONS: This case report suggests that potential fungal infection should be considered during the diagnostic workup of a mass in clinical practice. BioMed Central 2021-08-04 /pmc/articles/PMC8336084/ /pubmed/34348692 http://dx.doi.org/10.1186/s12879-021-06489-7 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Chen, Xue
Jia, Lin
Wu, Yongfeng
Chang, Jing
Zhang, Tong
Ma, Yingmin
Zhang, Yulin
A mass in the upper abdomen derived from Talaromyces marneffei infected lymphadenopathy: a case report
title A mass in the upper abdomen derived from Talaromyces marneffei infected lymphadenopathy: a case report
title_full A mass in the upper abdomen derived from Talaromyces marneffei infected lymphadenopathy: a case report
title_fullStr A mass in the upper abdomen derived from Talaromyces marneffei infected lymphadenopathy: a case report
title_full_unstemmed A mass in the upper abdomen derived from Talaromyces marneffei infected lymphadenopathy: a case report
title_short A mass in the upper abdomen derived from Talaromyces marneffei infected lymphadenopathy: a case report
title_sort mass in the upper abdomen derived from talaromyces marneffei infected lymphadenopathy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336084/
https://www.ncbi.nlm.nih.gov/pubmed/34348692
http://dx.doi.org/10.1186/s12879-021-06489-7
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