High-resolution Hi-C maps highlight multiscale 3D epigenome reprogramming during pancreatic cancer metastasis

BACKGROUND: Pancreatic cancer’s poor prognosis is caused by distal metastasis, which is associated with epigenetic changes. However, the role of the 3D epigenome in pancreatic cancer biology, especially its metastasis, remains unclear. METHODS: Here, we developed high-resolution 3D epigenomic maps o...

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Detalles Bibliográficos
Autores principales: Ren, Bo, Yang, Jinshou, Wang, Chengcheng, Yang, Gang, Wang, Huanyu, Chen, Yuan, Xu, Ruiyuan, Fan, Xuning, You, Lei, Zhang, Taiping, Zhao, Yupei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336101/
https://www.ncbi.nlm.nih.gov/pubmed/34348759
http://dx.doi.org/10.1186/s13045-021-01131-0

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