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Adult Blaschkitis With Lichenoid Features and Blood Eosinophilia
There have been many reports of congenital and acquired dermatoses that trail Blaschko lines. Lichen striatus is representative of an acquired cutaneous linear inflammatory dermatosis running along the lines of Blaschko, characterized histopathologically by the predominance of lichenoid infiltration...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336293/ https://www.ncbi.nlm.nih.gov/pubmed/34367837 http://dx.doi.org/10.7759/cureus.16846 |
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author | Al-Balbeesi, Amal |
author_facet | Al-Balbeesi, Amal |
author_sort | Al-Balbeesi, Amal |
collection | PubMed |
description | There have been many reports of congenital and acquired dermatoses that trail Blaschko lines. Lichen striatus is representative of an acquired cutaneous linear inflammatory dermatosis running along the lines of Blaschko, characterized histopathologically by the predominance of lichenoid infiltration. Adult blaschkitis, however, is considered under the same disease spectrum as lichen striatus and is characterized by a spongiotic reaction pattern. Few differences have been recognized between lichen striatus and adult blaschkitis such as age of onset, triggers, distribution, histopathology, and response to treatment. A case of male patient with adult blaschkitis presenting as unilateral asymptomatic erythematous edematous papules, papulovesicles, and plaques over Blaschko’s lines, in which skin biopsy revealed coexistent pathological features of lichen striatus and adult blaschkitis along with blood eosinophilia, has been presented here. This may add to the cumulative evidence on the pathogenesis of adult blaschkitis as an allergic reaction to an unknown inciting allergen. Evidence to consider adult blaschkitis as part of the lichen striatus spectrum is growing. Triggers for such skin reactions remain diverse. This case presentation suggests that adult blaschkitis could be triggered by an allergic response evidenced by the blood eosinophilia when other causes of eosinophilia are excluded. |
format | Online Article Text |
id | pubmed-8336293 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-83362932021-08-06 Adult Blaschkitis With Lichenoid Features and Blood Eosinophilia Al-Balbeesi, Amal Cureus Dermatology There have been many reports of congenital and acquired dermatoses that trail Blaschko lines. Lichen striatus is representative of an acquired cutaneous linear inflammatory dermatosis running along the lines of Blaschko, characterized histopathologically by the predominance of lichenoid infiltration. Adult blaschkitis, however, is considered under the same disease spectrum as lichen striatus and is characterized by a spongiotic reaction pattern. Few differences have been recognized between lichen striatus and adult blaschkitis such as age of onset, triggers, distribution, histopathology, and response to treatment. A case of male patient with adult blaschkitis presenting as unilateral asymptomatic erythematous edematous papules, papulovesicles, and plaques over Blaschko’s lines, in which skin biopsy revealed coexistent pathological features of lichen striatus and adult blaschkitis along with blood eosinophilia, has been presented here. This may add to the cumulative evidence on the pathogenesis of adult blaschkitis as an allergic reaction to an unknown inciting allergen. Evidence to consider adult blaschkitis as part of the lichen striatus spectrum is growing. Triggers for such skin reactions remain diverse. This case presentation suggests that adult blaschkitis could be triggered by an allergic response evidenced by the blood eosinophilia when other causes of eosinophilia are excluded. Cureus 2021-08-03 /pmc/articles/PMC8336293/ /pubmed/34367837 http://dx.doi.org/10.7759/cureus.16846 Text en Copyright © 2021, Al-Balbeesi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Dermatology Al-Balbeesi, Amal Adult Blaschkitis With Lichenoid Features and Blood Eosinophilia |
title | Adult Blaschkitis With Lichenoid Features and Blood Eosinophilia |
title_full | Adult Blaschkitis With Lichenoid Features and Blood Eosinophilia |
title_fullStr | Adult Blaschkitis With Lichenoid Features and Blood Eosinophilia |
title_full_unstemmed | Adult Blaschkitis With Lichenoid Features and Blood Eosinophilia |
title_short | Adult Blaschkitis With Lichenoid Features and Blood Eosinophilia |
title_sort | adult blaschkitis with lichenoid features and blood eosinophilia |
topic | Dermatology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336293/ https://www.ncbi.nlm.nih.gov/pubmed/34367837 http://dx.doi.org/10.7759/cureus.16846 |
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