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Adult Blaschkitis With Lichenoid Features and Blood Eosinophilia

There have been many reports of congenital and acquired dermatoses that trail Blaschko lines. Lichen striatus is representative of an acquired cutaneous linear inflammatory dermatosis running along the lines of Blaschko, characterized histopathologically by the predominance of lichenoid infiltration...

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Autor principal: Al-Balbeesi, Amal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336293/
https://www.ncbi.nlm.nih.gov/pubmed/34367837
http://dx.doi.org/10.7759/cureus.16846
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author Al-Balbeesi, Amal
author_facet Al-Balbeesi, Amal
author_sort Al-Balbeesi, Amal
collection PubMed
description There have been many reports of congenital and acquired dermatoses that trail Blaschko lines. Lichen striatus is representative of an acquired cutaneous linear inflammatory dermatosis running along the lines of Blaschko, characterized histopathologically by the predominance of lichenoid infiltration. Adult blaschkitis, however, is considered under the same disease spectrum as lichen striatus and is characterized by a spongiotic reaction pattern. Few differences have been recognized between lichen striatus and adult blaschkitis such as age of onset, triggers, distribution, histopathology, and response to treatment. A case of male patient with adult blaschkitis presenting as unilateral asymptomatic erythematous edematous papules, papulovesicles, and plaques over Blaschko’s lines, in which skin biopsy revealed coexistent pathological features of lichen striatus and adult blaschkitis along with blood eosinophilia, has been presented here. This may add to the cumulative evidence on the pathogenesis of adult blaschkitis as an allergic reaction to an unknown inciting allergen. Evidence to consider adult blaschkitis as part of the lichen striatus spectrum is growing. Triggers for such skin reactions remain diverse. This case presentation suggests that adult blaschkitis could be triggered by an allergic response evidenced by the blood eosinophilia when other causes of eosinophilia are excluded.
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spelling pubmed-83362932021-08-06 Adult Blaschkitis With Lichenoid Features and Blood Eosinophilia Al-Balbeesi, Amal Cureus Dermatology There have been many reports of congenital and acquired dermatoses that trail Blaschko lines. Lichen striatus is representative of an acquired cutaneous linear inflammatory dermatosis running along the lines of Blaschko, characterized histopathologically by the predominance of lichenoid infiltration. Adult blaschkitis, however, is considered under the same disease spectrum as lichen striatus and is characterized by a spongiotic reaction pattern. Few differences have been recognized between lichen striatus and adult blaschkitis such as age of onset, triggers, distribution, histopathology, and response to treatment. A case of male patient with adult blaschkitis presenting as unilateral asymptomatic erythematous edematous papules, papulovesicles, and plaques over Blaschko’s lines, in which skin biopsy revealed coexistent pathological features of lichen striatus and adult blaschkitis along with blood eosinophilia, has been presented here. This may add to the cumulative evidence on the pathogenesis of adult blaschkitis as an allergic reaction to an unknown inciting allergen. Evidence to consider adult blaschkitis as part of the lichen striatus spectrum is growing. Triggers for such skin reactions remain diverse. This case presentation suggests that adult blaschkitis could be triggered by an allergic response evidenced by the blood eosinophilia when other causes of eosinophilia are excluded. Cureus 2021-08-03 /pmc/articles/PMC8336293/ /pubmed/34367837 http://dx.doi.org/10.7759/cureus.16846 Text en Copyright © 2021, Al-Balbeesi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Al-Balbeesi, Amal
Adult Blaschkitis With Lichenoid Features and Blood Eosinophilia
title Adult Blaschkitis With Lichenoid Features and Blood Eosinophilia
title_full Adult Blaschkitis With Lichenoid Features and Blood Eosinophilia
title_fullStr Adult Blaschkitis With Lichenoid Features and Blood Eosinophilia
title_full_unstemmed Adult Blaschkitis With Lichenoid Features and Blood Eosinophilia
title_short Adult Blaschkitis With Lichenoid Features and Blood Eosinophilia
title_sort adult blaschkitis with lichenoid features and blood eosinophilia
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336293/
https://www.ncbi.nlm.nih.gov/pubmed/34367837
http://dx.doi.org/10.7759/cureus.16846
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