A Rare Case of Inadvertent Iatrogenic Osmotic Demyelination Syndrome

A 73-year-old African American male presented with altered mental status, severe hyperglycemia, and acute kidney injury. His metabolic derangements including hyperglycemia and hyponatremia were initially thought to be the cause of his encephalopathy. While managing his hyperglycemic hyperosmolar non...

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Detalles Bibliográficos
Autores principales: Akinbamijo, Kasopefoluwa O, Malmberg, Ifeoluwa R, Griffith, Candace, Aluko, Oluwatomisin, Thirumaran, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Endocrinology/Diabetes/Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336377/
https://www.ncbi.nlm.nih.gov/pubmed/34367787
http://dx.doi.org/10.7759/cureus.16180
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author Akinbamijo, Kasopefoluwa O
Malmberg, Ifeoluwa R
Griffith, Candace
Aluko, Oluwatomisin
Thirumaran, Rajesh
author_facet Akinbamijo, Kasopefoluwa O
Malmberg, Ifeoluwa R
Griffith, Candace
Aluko, Oluwatomisin
Thirumaran, Rajesh
author_sort Akinbamijo, Kasopefoluwa O
collection PubMed
description A 73-year-old African American male presented with altered mental status, severe hyperglycemia, and acute kidney injury. His metabolic derangements including hyperglycemia and hyponatremia were initially thought to be the cause of his encephalopathy. While managing his hyperglycemic hyperosmolar non-ketotic state, he received intravenous rehydration with almost three times his physiologic requirement for normalization of his electrolyte abnormalities. After the correction of the metabolic derangements, he remained confused with dysarthria and labile mood. Magnetic resonance imaging of the brain revealed osmotic demyelination syndrome.
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spelling pubmed-83363772021-08-06 A Rare Case of Inadvertent Iatrogenic Osmotic Demyelination Syndrome Akinbamijo, Kasopefoluwa O Malmberg, Ifeoluwa R Griffith, Candace Aluko, Oluwatomisin Thirumaran, Rajesh Cureus Endocrinology/Diabetes/Metabolism A 73-year-old African American male presented with altered mental status, severe hyperglycemia, and acute kidney injury. His metabolic derangements including hyperglycemia and hyponatremia were initially thought to be the cause of his encephalopathy. While managing his hyperglycemic hyperosmolar non-ketotic state, he received intravenous rehydration with almost three times his physiologic requirement for normalization of his electrolyte abnormalities. After the correction of the metabolic derangements, he remained confused with dysarthria and labile mood. Magnetic resonance imaging of the brain revealed osmotic demyelination syndrome. Cureus 2021-07-04 /pmc/articles/PMC8336377/ /pubmed/34367787 http://dx.doi.org/10.7759/cureus.16180 Text en Copyright © 2021, Akinbamijo et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Akinbamijo, Kasopefoluwa O
Malmberg, Ifeoluwa R
Griffith, Candace
Aluko, Oluwatomisin
Thirumaran, Rajesh
A Rare Case of Inadvertent Iatrogenic Osmotic Demyelination Syndrome
title A Rare Case of Inadvertent Iatrogenic Osmotic Demyelination Syndrome
title_full A Rare Case of Inadvertent Iatrogenic Osmotic Demyelination Syndrome
title_fullStr A Rare Case of Inadvertent Iatrogenic Osmotic Demyelination Syndrome
title_full_unstemmed A Rare Case of Inadvertent Iatrogenic Osmotic Demyelination Syndrome
title_short A Rare Case of Inadvertent Iatrogenic Osmotic Demyelination Syndrome
title_sort rare case of inadvertent iatrogenic osmotic demyelination syndrome
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336377/
https://www.ncbi.nlm.nih.gov/pubmed/34367787
http://dx.doi.org/10.7759/cureus.16180
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