Safety and Immunogenicity of a Recombinant Tetanus Vaccine in Healthy Adults in China: A Randomized, Double‐Blind, Dose Escalation, Placebo‐ and Positive‐Controlled, Phase 1/2 Trial

Tetanus is a fatal but vaccine‐preventable disease. The currently available tetanus vaccines are tetanus toxoid (TT)‐based. Although these vaccines are generally effective, challenges in vaccine development and access remain. A randomized, double‐blind, dose escalation, placebo‐ and positive‐control...

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Detalles Bibliográficos
Autores principales: Xu, Xiaowei, Yu, Rui, Xiao, Lanlan, Wang, Jie, Yu, Meihong, Xu, Junjie, Tan, Yajun, Ma, Xiao, Wu, Xiaoxin, Lian, Jiangshan, Huang, Kaizhou, Ouyang, Xiaoxi, Bi, Sheng, Wu, Shipo, Wang, Xiaoyan, Jin, Jiandi, Yu, Ling, Zhang, Huafen, Wei, Qi, Shi, Jinfa, Chen, Wei, Li, Lanjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336487/
https://www.ncbi.nlm.nih.gov/pubmed/34081408
http://dx.doi.org/10.1002/advs.202002751

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