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Modeling drug combination effects via latent tensor reconstruction

MOTIVATION: Combination therapies have emerged as a powerful treatment modality to overcome drug resistance and improve treatment efficacy. However, the number of possible drug combinations increases very rapidly with the number of individual drugs in consideration, which makes the comprehensive exp...

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Detalles Bibliográficos
Autores principales: Wang, Tianduanyi, Szedmak, Sandor, Wang, Haishan, Aittokallio, Tero, Pahikkala, Tapio, Cichonska, Anna, Rousu, Juho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336593/
https://www.ncbi.nlm.nih.gov/pubmed/34252952
http://dx.doi.org/10.1093/bioinformatics/btab308

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