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Exploring regulation and function of dopamine D3 receptors in alcohol use disorder. A PET [(11)C]-(+)-PHNO study

Preclinical studies support an important role of dopamine D3 receptors (DRD3s) in alcohol use disorder (AUD). In animals, voluntary alcohol consumption increases DRD3 expression, and pharmacological blockade of DRD3s attenuates alcohol self-administration and reinstatement of alcohol seeking. Howeve...

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Detalles Bibliográficos
Autores principales:	Chukwueke, Chidera C., Nona, Christina N., McPhee, Matthew D., Mansouri, Esmaeil, Rubin-Kahana, Dafna S., Martinez, Diana, Boileau, Isabelle, Hendershot, Christian S., Le Foll, Bernard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336665/ https://www.ncbi.nlm.nih.gov/pubmed/34349232 http://dx.doi.org/10.1038/s41386-021-01095-2

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