Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease

The SARS-CoV-2 coronavirus has led to a pandemic with millions of people affected. The present study finds that risk-factors for severe COVID-19 disease courses, i.e. male sex, older age and sedentary life style are associated with higher prostaglandin E2 (PGE2) serum levels in blood samples from un...

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Detalles Bibliográficos
Autores principales: Ricke-Hoch, Melanie, Stelling, Elisabeth, Lasswitz, Lisa, Gunesch, Antonia P., Kasten, Martina, Zapatero-Belinchón, Francisco J., Brogden, Graham, Gerold, Gisa, Pietschmann, Thomas, Montiel, Virginie, Balligand, Jean-Luc, Facciotti, Federica, Hirsch, Emilio, Gausepohl, Thomas, Elbahesh, Husni, Rimmelzwaan, Guus F., Höfer, Anne, Kühnel, Mark P., Jonigk, Danny, Eigendorf, Julian, Tegtbur, Uwe, Mink, Lena, Scherr, Michaela, Illig, Thomas, Schambach, Axel, Pfeffer, Tobias J., Hilfiker, Andres, Haverich, Axel, Hilfiker-Kleiner, Denise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336874/
https://www.ncbi.nlm.nih.gov/pubmed/34347801
http://dx.doi.org/10.1371/journal.pone.0255335

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