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BMAL1 dephosphorylation determines the pace of the circadian clock

In mammals, virtually all body cells harbor cell-autonomous and self-sustained circadian oscillators that rely on delayed negative feedback loops in gene expression. Transcriptional activation and repression play a major role in keeping these clocks ticking, but numerous post-translational mechanism...

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Detalles Bibliográficos
Autor principal: Schibler, Ueli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336897/
https://www.ncbi.nlm.nih.gov/pubmed/34341001
http://dx.doi.org/10.1101/gad.348801.121