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BMAL1 dephosphorylation determines the pace of the circadian clock
In mammals, virtually all body cells harbor cell-autonomous and self-sustained circadian oscillators that rely on delayed negative feedback loops in gene expression. Transcriptional activation and repression play a major role in keeping these clocks ticking, but numerous post-translational mechanism...
Autor principal: | Schibler, Ueli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336897/ https://www.ncbi.nlm.nih.gov/pubmed/34341001 http://dx.doi.org/10.1101/gad.348801.121 |
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