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Repurposing RNA sequencing for discovery of RNA modifications in clinical cohorts

The study of RNA modifications in large clinical cohorts can reveal relationships between the epitranscriptome and human diseases, although this is especially challenging. We developed ModTect (https://github.com/ktan8/ModTect), a statistical framework to identify RNA modifications de novo by standa...

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Detalles Bibliográficos
Autores principales:	Tan, Kar-Tong, Ding, Ling-Wen, Wu, Chan-Shuo, Tenen, Daniel G., Yang, Henry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336963/ https://www.ncbi.nlm.nih.gov/pubmed/34348892 http://dx.doi.org/10.1126/sciadv.abd2605

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