Cargando…

Picroside II Improves Severe Acute Pancreatitis-Induced Hepatocellular Injury in Rats by Affecting JAK2/STAT3 Phosphorylation Signaling

Picroside II is an important ingredient agent in Traditional Chinese medicine and hoped to reduce hepatocellular injury caused by severe acute pancreatitis (SAP). An SAP-induced hepatocellular injury model was established in rats by using pentobarbital sodium. 27 rats were divided into 3 groups: the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Piao, Xuehua, Sui, Xiaodan, Liu, Baohai, Cui, Tingfang, Qi, Zinan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8337114/ https://www.ncbi.nlm.nih.gov/pubmed/34368363 http://dx.doi.org/10.1155/2021/9945149

Ejemplares similares

Picroside II Shows Protective Functions for Severe Acute Pancreatitis in Rats by Preventing NF-κB-Dependent Autophagy
por: Piao, Xuehua, et al.
Publicado: (2017)

Picroside II Improves Severe Acute Pancreatitis-Induced Intestinal Barrier Injury by Inactivating Oxidative and Inflammatory TLR4-Dependent PI3K/AKT/NF-κB Signaling and Improving Gut Microbiota
por: Piao, Xuehua, et al.
Publicado: (2020)

Hydrostatin-SN10 Ameliorates Pancreatitis-Induced Lung Injury by Affecting IL-6-Induced JAK2/STAT3-Associated Inflammation and Oxidative Stress
por: Piao, Xuehua, et al.
Publicado: (2019)

Picroside I and Picroside II from Tissue Cultures of Picrorhiza kurroa
por: Ganeshkumar, Yamjala, et al.
Publicado: (2017)

Kuijieyuan Decoction Improved Intestinal Barrier Injury of Ulcerative Colitis by Affecting TLR4-Dependent PI3K/AKT/NF-κB Oxidative and Inflammatory Signaling and Gut Microbiota
por: Liu, Baohai, et al.
Publicado: (2020)

Protective effect of picroside II on myocardial ischemia reperfusion injury in rats
por: Wu, Nan, et al.
Publicado: (2014)

Effect of picroside II on hind limb ischemia reperfusion injury in rats
por: Kılıç, Yiğit, et al.
Publicado: (2017)

Neuroprotective Properties of Picroside II in a Rat Model of Focal Cerebral Ischemia
por: Li, Qin, et al.
Publicado: (2010)

Optimal therapeutic dose and time window of picroside II in cerebral ischemic injury
por: Liu, Guangyi, et al.
Publicado: (2014)

Effect of picroside II on apoptosis induced by renal ischemia/reperfusion injury in rats
por: WANG, LEI, et al.
Publicado: (2015)

Neutrophilic Lung Inflammation Suppressed by Picroside II Is Associated with TGF-β Signaling
por: Noh, Soohwan, et al.
Publicado: (2015)

JAK/STAT signaling in hepatocellular carcinoma
por: Hin Tang, Justin Jit, et al.
Publicado: (2020)

1-Deoxynojirimycin (DNJ) Ameliorates Indomethacin-Induced Gastric Ulcer in Mice by Affecting NF-kappaB Signaling Pathway
por: Piao, Xuehua, et al.
Publicado: (2018)

Root Extract of Polygonum cuspidatum Siebold & Zucc. Ameliorates DSS-Induced Ulcerative Colitis by Affecting NF-kappaB Signaling Pathway in a Mouse Model via Synergistic Effects of Polydatin, Resveratrol, and Emodin
por: Liu, Baohai, et al.
Publicado: (2018)

Intervention by picroside II on FFAs induced lipid accumulation and lipotoxicity in HepG2 cells
por: Dhami-Shah, Hiteshi, et al.
Publicado: (2021)

Mediator Kinase Phosphorylation of STAT1 S727 Promotes Growth of Neoplasms With JAK-STAT Activation
por: Nitulescu, Ioana I., et al.
Publicado: (2017)

Alternative ways of modulating JAK-STAT pathway: Looking beyond phosphorylation
por: Timofeeva, Olga A., et al.
Publicado: (2012)

Protein Inhibitor of Activated STAT (PIAS) Negatively Regulates the JAK/STAT Pathway by Inhibiting STAT Phosphorylation and Translocation
por: Niu, Guo-Juan, et al.
Publicado: (2018)

Primary Study for the Therapeutic Dose and Time Window of Picroside II in Treating Cerebral Ischemic Injury in Rats
por: Pei, Haitao, et al.
Publicado: (2012)

Picroside II protects myocardium from ischemia/reperfusion-induced injury through inhibition of the inflammatory response
por: Li, Jian-Zhe, et al.
Publicado: (2016)

Picroside II attenuates hyperhomocysteinemia‐induced endothelial injury by reducing inflammation, oxidative stress and cell apoptosis
por: Wang, Yunkai, et al.
Publicado: (2018)

Anti-inflammation effects of picroside 2 in cerebral ischemic injury rats
por: Guo, Yunliang, et al.
Publicado: (2010)

Activating JAK1 mutation may predict the sensitivity of JAK-STAT inhibition in hepatocellular carcinoma
por: Yang, Shuqun, et al.
Publicado: (2015)

Effect of picroside II on erythrocyte deformability and lipid peroxidation in rats subjected to hind limb ischemia reperfusion injury
por: Çomu, Faruk Metin, et al.
Publicado: (2016)

Picroside II protects the blood-brain barrier by inhibiting the oxidative signaling pathway in cerebral ischemia-reperfusion injury
por: Zhai, Li, et al.
Publicado: (2017)

The neuroprotective effect of picroside II via regulating the expression of myelin basic protein after cerebral ischemia injury in rats
por: Zhao, Li, et al.
Publicado: (2014)

Picroside II Inhibits Neuronal Apoptosis and Improves the Morphology and Structure of Brain Tissue following Cerebral Ischemic Injury in Rats
por: Wang, Tingting, et al.
Publicado: (2015)

JAKs and STATs in chemoresistance
por: Costa-Pereira, Ana P
Publicado: (2010)

JAK-STAT and feeding
por: Ladyman, Sharon R., et al.
Publicado: (2013)

The Interaction of the IFNγ/JAK/STAT1 and JAK/STAT3 Signalling Pathways in EGFR-Mutated Lung Adenocarcinoma Cells
por: Han, Yaguang, et al.
Publicado: (2022)

Picroside II attenuates fatty acid accumulation in HepG2 cells via modulation of fatty acid uptake and synthesis
por: Dhami-Shah, Hiteshi, et al.
Publicado: (2018)

Picroside II attenuates ischemia/reperfusion testicular injury by alleviating oxidative stress and apoptosis through reducing nitric oxide synthesis
por: Li, Yanze, et al.
Publicado: (2019)

Jak-Stat Signaling Induced by Interleukin-6 Family Cytokines in Hepatocellular Carcinoma
por: Lokau, Juliane, et al.
Publicado: (2019)

Dihydrotanshinone Inhibits Hepatocellular Carcinoma by Suppressing the JAK2/STAT3 Pathway
por: Hu, Xue, et al.
Publicado: (2021)

A JAK/STAT invasion
por: Wells, William A.
Publicado: (2002)

JAK-STAT and bone metabolism
por: Li, Jiliang
Publicado: (2013)

The Drosophila JAK-STAT pathway
por: Zeidler, Martin P, et al.
Publicado: (2013)

Evolution of the JAK-STAT pathway
por: Liongue, Clifford, et al.
Publicado: (2013)

The JAK-STAT pathway at 20
por: Darnell, Jr., James E.
Publicado: (2012)

JAK-STAT in lymphoproliferative disorders
por: Rabadan, Raul, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_n9ntnihft1q923hrn71taibnf1