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Deficiency of ROS-Activated TRPM2 Channel Protects Neurons from Cerebral Ischemia-Reperfusion Injury through Upregulating Autophagy

Cerebral ischemia-reperfusion (I-R) transiently increased autophagy by producing excessively reactive oxygen species (ROS); on the other hand, activated autophagy would remove ROS-damaged mitochondria and proteins, which led to cell survival. However, the regulation mechanism of autophagy activity d...

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Detalles Bibliográficos
Autores principales:	Hu, Xupang, Wu, Lijuan, Liu, Xingyu, Zhang, Yi, Xu, Min, Fang, Qiuyuan, Lu, Lin, Niu, Jianguo, Abd El-Aziz, Tarek Mohamed, Jiang, Lin-Hua, Li, Fangfang, Yang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8337124/ https://www.ncbi.nlm.nih.gov/pubmed/34367466 http://dx.doi.org/10.1155/2021/7356266

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