Oncolytic Vaccinia Virus Gene Modification and Cytokine Expression Effects on Tumor Infection, Immune Response, and Killing

Oncolytic vaccinia viruses have promising efficacy and safety profiles in cancer therapy. Although antitumor activity can be increased by manipulating viral genes, the relative efficacy of individual modifications has been difficult to assess without side-by-side comparisons. This study sought to co...

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Detalles Bibliográficos
Autores principales: Inoue, Tomoyoshi, Byrne, Thomas, Inoue, Mitsuko, Tait, Madeline E., Wall, Patrick, Wang, Annabel, Dermyer, Michael R., Laklai, Hanane, Binder, Joseph J., Lees, Clare, Hollingsworth, Robert, Maruri-Avidal, Liliana, Kirn, David H., McDonald, Donald M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Models and Technologies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338778/
https://www.ncbi.nlm.nih.gov/pubmed/34045231
http://dx.doi.org/10.1158/1535-7163.MCT-20-0863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338778/
https://www.ncbi.nlm.nih.gov/pubmed/34045231
http://dx.doi.org/10.1158/1535-7163.MCT-20-0863

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