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Sustained effects of rapidly-acting antidepressants require BDNF-dependent MeCP2 phosphorylation
The rapidly acting antidepressants ketamine and scopolamine exert behavioral effects that can last several days to weeks in some patients. The molecular mechanisms underlying the maintenance of these antidepressant effects are unknown. Here, we show that methyl-CpG-binding protein 2 (MeCP2) phosphor...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338784/ https://www.ncbi.nlm.nih.gov/pubmed/34183865 http://dx.doi.org/10.1038/s41593-021-00868-8 |