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Functional estrogen receptor signaling pathway activity in high-grade serous ovarian carcinoma as compared to estrogen receptor protein expression by immunohistochemistry

PURPOSE: Anti-estrogen therapy may be used as a palliative treatment option in high-grade serous ovarian carcinomas (HGSC). However, clinical implementation is limited as the use of estrogen receptor (ER) protein expression by immunohistochemistry remains insufficient in predicting therapy response....

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Detalles Bibliográficos
Autores principales: van der Ploeg, Phyllis, van Lieshout, Laura A. M., van de Stolpe, Anja, Bosch, Steven L., Lentjes-Beer, Marjolein H. F. M., Bekkers, Ruud L. M., Piek, Jurgen M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338831/
https://www.ncbi.nlm.nih.gov/pubmed/33723801
http://dx.doi.org/10.1007/s13402-021-00600-5