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Survivin drives tumor-associated macrophage reprogramming: a novel mechanism with potential impact for obesity

PURPOSE: Recent studies point to adipose-derived stem cells (ASCs) as a link between obesity and cancer. We aimed to determine whether survivin, which is highly secreted by ASCs from subjects with obesity, might drive a pro-tumoral phenotype in macrophages. METHODS: The effect of ASC conditioned med...

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Detalles Bibliográficos
Autores principales: Benaiges, E., Ceperuelo-Mallafré, V., Madeira, A., Bosch, R., Núñez-Roa, C., Ejarque, M., Maymó-Masip, E., Huber-Ruano, I., Lejeune, M., Vendrell, J., Fernández-Veledo, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8338861/
https://www.ncbi.nlm.nih.gov/pubmed/33710603
http://dx.doi.org/10.1007/s13402-021-00597-x

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