Pueraria mirifica, an estrogenic tropical herb, unveiled the severity of Type 1 LQTS caused by KCNQ1‐T587M

After taking an estrogen‐containing supplement derived from a tropical plant Pueraria mirifica, a 24‐year‐old woman presented marked QT prolongation and repetitive torsade de pointes. The patient was found to carry a heterozygous KCNQ1‐T587M mutation. This is the first report on Pueraria mirifica‐re...

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Autores principales: Kashiwa, Asami, Hosaka, Yukio, Takahashi, Kazuyoshi, Ohno, Seiko, Wada, Yuko, Makiyama, Takeru, Oda, Hirotaka, Horie, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Cardiac Arrhythmia Spot Light
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339079/
https://www.ncbi.nlm.nih.gov/pubmed/34386142
http://dx.doi.org/10.1002/joa3.12576
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author Kashiwa, Asami
Hosaka, Yukio
Takahashi, Kazuyoshi
Ohno, Seiko
Wada, Yuko
Makiyama, Takeru
Oda, Hirotaka
Horie, Minoru
author_facet Kashiwa, Asami
Hosaka, Yukio
Takahashi, Kazuyoshi
Ohno, Seiko
Wada, Yuko
Makiyama, Takeru
Oda, Hirotaka
Horie, Minoru
author_sort Kashiwa, Asami
collection PubMed
description After taking an estrogen‐containing supplement derived from a tropical plant Pueraria mirifica, a 24‐year‐old woman presented marked QT prolongation and repetitive torsade de pointes. The patient was found to carry a heterozygous KCNQ1‐T587M mutation. This is the first report on Pueraria mirifica‐related acquired long QT syndrome. [Image: see text]
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spelling pubmed-83390792021-08-11 Pueraria mirifica, an estrogenic tropical herb, unveiled the severity of Type 1 LQTS caused by KCNQ1‐T587M Kashiwa, Asami Hosaka, Yukio Takahashi, Kazuyoshi Ohno, Seiko Wada, Yuko Makiyama, Takeru Oda, Hirotaka Horie, Minoru J Arrhythm Cardiac Arrhythmia Spot Light After taking an estrogen‐containing supplement derived from a tropical plant Pueraria mirifica, a 24‐year‐old woman presented marked QT prolongation and repetitive torsade de pointes. The patient was found to carry a heterozygous KCNQ1‐T587M mutation. This is the first report on Pueraria mirifica‐related acquired long QT syndrome. [Image: see text] John Wiley and Sons Inc. 2021-06-14 /pmc/articles/PMC8339079/ /pubmed/34386142 http://dx.doi.org/10.1002/joa3.12576 Text en © 2021 The Authors. Journal of Arrhythmia published by John Wiley & Sons Australia, Ltd on behalf of Japanese Heart Rhythm Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Cardiac Arrhythmia Spot Light
Kashiwa, Asami
Hosaka, Yukio
Takahashi, Kazuyoshi
Ohno, Seiko
Wada, Yuko
Makiyama, Takeru
Oda, Hirotaka
Horie, Minoru
Pueraria mirifica, an estrogenic tropical herb, unveiled the severity of Type 1 LQTS caused by KCNQ1‐T587M
title Pueraria mirifica, an estrogenic tropical herb, unveiled the severity of Type 1 LQTS caused by KCNQ1‐T587M
title_full Pueraria mirifica, an estrogenic tropical herb, unveiled the severity of Type 1 LQTS caused by KCNQ1‐T587M
title_fullStr Pueraria mirifica, an estrogenic tropical herb, unveiled the severity of Type 1 LQTS caused by KCNQ1‐T587M
title_full_unstemmed Pueraria mirifica, an estrogenic tropical herb, unveiled the severity of Type 1 LQTS caused by KCNQ1‐T587M
title_short Pueraria mirifica, an estrogenic tropical herb, unveiled the severity of Type 1 LQTS caused by KCNQ1‐T587M
title_sort pueraria mirifica, an estrogenic tropical herb, unveiled the severity of type 1 lqts caused by kcnq1‐t587m
topic Cardiac Arrhythmia Spot Light
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339079/
https://www.ncbi.nlm.nih.gov/pubmed/34386142
http://dx.doi.org/10.1002/joa3.12576
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