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Intradermal vaccination of live attenuated influenza vaccine protects mice against homologous and heterologous influenza challenges

We previously developed a temperature-sensitive, and NS1 gene deleted live attenuated influenza vaccine (DelNS1-LAIV) and demonstrated its potent protective efficacy in intranasally vaccinated mice. Here we investigated whether intradermal (i.d.) vaccination induces protective immunity. Our results...

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Detalles Bibliográficos
Autores principales:	Lee, Andrew Chak-Yiu, Zhang, Anna Jinxia, Li, Can, Chen, Yanxia, Liu, Feifei, Zhao, Yan, Chu, Hin, Fong, Carol Ho-Yan, Wang, Pui, Lau, Siu-Ying, To, Kelvin Kai-Wang, Chen, Honglin, Yuen, Kwok-Yung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339132/ https://www.ncbi.nlm.nih.gov/pubmed/34349128 http://dx.doi.org/10.1038/s41541-021-00359-8

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