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Pimpinellin Inhibits Collagen-induced Platelet Aggregation and Activation Through Inhibiting Granule Secretion and PI3K/Akt Pathway

Pimpinellin is a coumarin-like compound extracted from the root of Toddalia asiatica. Its effects on platelet function has not been investigated. This study found that pimpinellin pretreatment effectively inhibited collagen-induced platelet aggregation, but did not alter ADP- and thrombin-induced ag...

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Detalles Bibliográficos
Autores principales:	Liu, Gang, Yuan, Zhaowei, Tian, Xiaoyun, Xiong, Xiuqin, Guo, Fang, Lin, Zihan, Qin, Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339208/ https://www.ncbi.nlm.nih.gov/pubmed/34366861 http://dx.doi.org/10.3389/fphar.2021.706363

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