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Evaluation of the Pharmacologic Treatment of COVID-19 Pandemic in Iraq

The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, or COVID-19) has been detrimental to human health, economy, and wellbeing. Little information is known on the epidemiology and outcome of the disease in a localized community within Iraq. We carried out an audit of confirmed...

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Autores principales: Darweesh, Omeed, Abdulrazzaq, Ghayth M., Al-Zidan, Radhwan N., Bebane, Pshtiwan, Merkhan, Marwan, Aldabbagh, Ruya, AlOmari, Nohad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339216/
https://www.ncbi.nlm.nih.gov/pubmed/34377628
http://dx.doi.org/10.1007/s40495-021-00262-9
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author Darweesh, Omeed
Abdulrazzaq, Ghayth M.
Al-Zidan, Radhwan N.
Bebane, Pshtiwan
Merkhan, Marwan
Aldabbagh, Ruya
AlOmari, Nohad
author_facet Darweesh, Omeed
Abdulrazzaq, Ghayth M.
Al-Zidan, Radhwan N.
Bebane, Pshtiwan
Merkhan, Marwan
Aldabbagh, Ruya
AlOmari, Nohad
author_sort Darweesh, Omeed
collection PubMed
description The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, or COVID-19) has been detrimental to human health, economy, and wellbeing. Little information is known on the epidemiology and outcome of the disease in a localized community within Iraq. We carried out an audit of confirmed cases of COVID-19 in the Kirkuk General Hospital. Data from the 20th of June to the 31st of July, 2020, were collected and analyzed. Suspected COVID-19 cases were confirmed by real-time polymerase chain reaction (RT-PCR). Data on clinical symptoms, age, and treatment protocols were analyzed concerning the outcome. Our study included a total of 200 individual confirmed COVID-19 patients. The majority of cases 55% (n = 110) displayed severe symptoms, while 32.5% (65 cases) and 12.5% (25 cases) of patients displayed moderate to mild symptoms, respectively. The rate of death in the referred patients was 5%. Most patients admitted to the hospital for treatment recovered and were discharged from the hospital within 5 to 30 days post-diagnosis. Statistical analysis revealed that patients treated with oseltamivir, hydroxychloroquine, and azithromycin in combination with vitamins C and D have shorter hospital stay compared to patients receiving the same therapeutic protocol in combination with steroids. Moreover, a higher mortality rate (4.5%) was observed in patients treated with oseltamivir, hydroxychloroquine, ceftriaxone, and steroids. This study highlights a significant relationship between age, secondary ailments, and the choice of medications as simple predictors of the outcome of COVID-19.
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spelling pubmed-83392162021-08-06 Evaluation of the Pharmacologic Treatment of COVID-19 Pandemic in Iraq Darweesh, Omeed Abdulrazzaq, Ghayth M. Al-Zidan, Radhwan N. Bebane, Pshtiwan Merkhan, Marwan Aldabbagh, Ruya AlOmari, Nohad Curr Pharmacol Rep Commentary The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, or COVID-19) has been detrimental to human health, economy, and wellbeing. Little information is known on the epidemiology and outcome of the disease in a localized community within Iraq. We carried out an audit of confirmed cases of COVID-19 in the Kirkuk General Hospital. Data from the 20th of June to the 31st of July, 2020, were collected and analyzed. Suspected COVID-19 cases were confirmed by real-time polymerase chain reaction (RT-PCR). Data on clinical symptoms, age, and treatment protocols were analyzed concerning the outcome. Our study included a total of 200 individual confirmed COVID-19 patients. The majority of cases 55% (n = 110) displayed severe symptoms, while 32.5% (65 cases) and 12.5% (25 cases) of patients displayed moderate to mild symptoms, respectively. The rate of death in the referred patients was 5%. Most patients admitted to the hospital for treatment recovered and were discharged from the hospital within 5 to 30 days post-diagnosis. Statistical analysis revealed that patients treated with oseltamivir, hydroxychloroquine, and azithromycin in combination with vitamins C and D have shorter hospital stay compared to patients receiving the same therapeutic protocol in combination with steroids. Moreover, a higher mortality rate (4.5%) was observed in patients treated with oseltamivir, hydroxychloroquine, ceftriaxone, and steroids. This study highlights a significant relationship between age, secondary ailments, and the choice of medications as simple predictors of the outcome of COVID-19. Springer International Publishing 2021-08-05 2021 /pmc/articles/PMC8339216/ /pubmed/34377628 http://dx.doi.org/10.1007/s40495-021-00262-9 Text en © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Commentary
Darweesh, Omeed
Abdulrazzaq, Ghayth M.
Al-Zidan, Radhwan N.
Bebane, Pshtiwan
Merkhan, Marwan
Aldabbagh, Ruya
AlOmari, Nohad
Evaluation of the Pharmacologic Treatment of COVID-19 Pandemic in Iraq
title Evaluation of the Pharmacologic Treatment of COVID-19 Pandemic in Iraq
title_full Evaluation of the Pharmacologic Treatment of COVID-19 Pandemic in Iraq
title_fullStr Evaluation of the Pharmacologic Treatment of COVID-19 Pandemic in Iraq
title_full_unstemmed Evaluation of the Pharmacologic Treatment of COVID-19 Pandemic in Iraq
title_short Evaluation of the Pharmacologic Treatment of COVID-19 Pandemic in Iraq
title_sort evaluation of the pharmacologic treatment of covid-19 pandemic in iraq
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339216/
https://www.ncbi.nlm.nih.gov/pubmed/34377628
http://dx.doi.org/10.1007/s40495-021-00262-9
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