Coronavirus Disease 2019 in a Patient With a Systemic Autoinflammatory Syndrome due to an NLRC4 Inflammasomopathy

The effect of autoinflammatory diseases on severe acute respiratory syndrome coronavirus 2 infection remains unknown. We report a case of coronavirus disease 2019 (COVID-19) in a patient with autoinflammation with infantile enterocolitis with inflammatory flares due to a mutation in the inflammasome...

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Autores principales: Duncan-Lowey, Jeffrey K, Chowdhary, Vaidehi, Dunne, Dana W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339282/
https://www.ncbi.nlm.nih.gov/pubmed/34377730
http://dx.doi.org/10.1093/ofid/ofab362
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author Duncan-Lowey, Jeffrey K
Chowdhary, Vaidehi
Dunne, Dana W
author_facet Duncan-Lowey, Jeffrey K
Chowdhary, Vaidehi
Dunne, Dana W
author_sort Duncan-Lowey, Jeffrey K
collection PubMed
description The effect of autoinflammatory diseases on severe acute respiratory syndrome coronavirus 2 infection remains unknown. We report a case of coronavirus disease 2019 (COVID-19) in a patient with autoinflammation with infantile enterocolitis with inflammatory flares due to a mutation in the inflammasome component NLRC4. This case highlights the role of immunosuppression in patients with autoinflammation with COVID-19.
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spelling pubmed-83392822021-08-09 Coronavirus Disease 2019 in a Patient With a Systemic Autoinflammatory Syndrome due to an NLRC4 Inflammasomopathy Duncan-Lowey, Jeffrey K Chowdhary, Vaidehi Dunne, Dana W Open Forum Infect Dis Brief Reports The effect of autoinflammatory diseases on severe acute respiratory syndrome coronavirus 2 infection remains unknown. We report a case of coronavirus disease 2019 (COVID-19) in a patient with autoinflammation with infantile enterocolitis with inflammatory flares due to a mutation in the inflammasome component NLRC4. This case highlights the role of immunosuppression in patients with autoinflammation with COVID-19. Oxford University Press 2021-07-05 /pmc/articles/PMC8339282/ /pubmed/34377730 http://dx.doi.org/10.1093/ofid/ofab362 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Duncan-Lowey, Jeffrey K
Chowdhary, Vaidehi
Dunne, Dana W
Coronavirus Disease 2019 in a Patient With a Systemic Autoinflammatory Syndrome due to an NLRC4 Inflammasomopathy
title Coronavirus Disease 2019 in a Patient With a Systemic Autoinflammatory Syndrome due to an NLRC4 Inflammasomopathy
title_full Coronavirus Disease 2019 in a Patient With a Systemic Autoinflammatory Syndrome due to an NLRC4 Inflammasomopathy
title_fullStr Coronavirus Disease 2019 in a Patient With a Systemic Autoinflammatory Syndrome due to an NLRC4 Inflammasomopathy
title_full_unstemmed Coronavirus Disease 2019 in a Patient With a Systemic Autoinflammatory Syndrome due to an NLRC4 Inflammasomopathy
title_short Coronavirus Disease 2019 in a Patient With a Systemic Autoinflammatory Syndrome due to an NLRC4 Inflammasomopathy
title_sort coronavirus disease 2019 in a patient with a systemic autoinflammatory syndrome due to an nlrc4 inflammasomopathy
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339282/
https://www.ncbi.nlm.nih.gov/pubmed/34377730
http://dx.doi.org/10.1093/ofid/ofab362
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