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Molecular basis for RASSF10/NPM/RNF2 feedback cascade–mediated regulation of gastric cancer cell proliferation

Ras-association domain family (RASSF) proteins are encoded by numerous tumor suppressor genes that frequently become silenced in human cancers. RASSF10 is downregulated by promoter hypermethylation in cancers and has been shown to inhibit cell proliferation; however, the molecular mechanism(s) remai...

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Detalles Bibliográficos
Autores principales: Lakshmi Ch, Naga Padma, Sivagnanam, Ananthi, Raja, Sebastian, Mahalingam, Sundarasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339327/
https://www.ncbi.nlm.nih.gov/pubmed/34224728
http://dx.doi.org/10.1016/j.jbc.2021.100935