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Molecular basis for RASSF10/NPM/RNF2 feedback cascade–mediated regulation of gastric cancer cell proliferation
Ras-association domain family (RASSF) proteins are encoded by numerous tumor suppressor genes that frequently become silenced in human cancers. RASSF10 is downregulated by promoter hypermethylation in cancers and has been shown to inhibit cell proliferation; however, the molecular mechanism(s) remai...
Autores principales: | Lakshmi Ch, Naga Padma, Sivagnanam, Ananthi, Raja, Sebastian, Mahalingam, Sundarasamy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339327/ https://www.ncbi.nlm.nih.gov/pubmed/34224728 http://dx.doi.org/10.1016/j.jbc.2021.100935 |
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