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Beyond PKA: Evolutionary and structural insights that define a docking and dimerization domain superfamily

Protein-interaction domains can create unique macromolecular complexes that drive evolutionary innovation. By combining bioinformatic and phylogenetic analyses with structural approaches, we have discovered that the docking and dimerization (D/D) domain of the PKA regulatory subunit is an ancient an...

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Detalles Bibliográficos
Autores principales:	Dahlin, Heather R., Zheng, Ning, Scott, John D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339350/ https://www.ncbi.nlm.nih.gov/pubmed/34256050 http://dx.doi.org/10.1016/j.jbc.2021.100927

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