Cargando…

SARS-CoV-2 viral load at presentation to hospital is independently associated with the risk of death

Objectives Previous studies have suggested that SARS-CoV-2 viral load, measured on upper respiratory tract samples at presentation to hospital using PCR Cycle threshold (Ct) value, has prognostic utility. However, these studies have not comprehensively adjusted for factors known to be intimately rel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tanner, Alex R, Phan, Hang, Brendish, Nathan J, Borca, Florina, Beard, Kate R, Poole, Stephen, W Clark, Tristan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The British Infection Association. Published by Elsevier Ltd. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339449/ https://www.ncbi.nlm.nih.gov/pubmed/34363885 http://dx.doi.org/10.1016/j.jinf.2021.08.003

Ejemplares similares

FebriDx host response point-of-care testing improves patient triage for coronavirus disease 2019 (COVID-19) in the emergency department
por: Mansbridge, Christopher T., et al.
Publicado: (2022)

FebriDx host response point-of-care testing improves patient triage for coronavirus disease 2019 (COVID-19) in the emergency department – ADDENDUM
por: Mansbridge, Christopher T., et al.
Publicado: (2022)

Routine molecular point-of-care testing for SARS-CoV-2 reduces hospital-acquired COVID-19
por: Livingstone, Robert, et al.
Publicado: (2022)

Clinical characteristics, symptoms and outcomes of 1054 adults presenting to hospital with suspected COVID-19: A comparison of patients with and without SARS-CoV-2 infection
por: Brendish, Nathan J, et al.
Publicado: (2020)

Physical distancing in schools for SARS-CoV-2 and the resurgence of rhinovirus
por: Poole, Stephen, et al.
Publicado: (2020)

654. Evaluation of the Febridx Host Response Point-of-Care Test to Differentiate Viral From Bacterial Etiology in Adults Hospitalized with Acute Respiratory Illness During Influenza Season
por: Beard, Kate, et al.
Publicado: (2019)

Increase in circulation of non-SARS-CoV-2 respiratory viruses following easing of social distancing is associated with increasing hospital attendance
por: Tanner, Alex R, et al.
Publicado: (2021)

1717. The Impact of Routine Molecular Point-of-care Testing for Gastrointestinal Pathogens in Adults Hospitalized With Suspected Gastroenteritis: Results of a Pragmatic Randomized Controlled Trial (GastroPOC)
por: Malachira, Ahalya, et al.
Publicado: (2018)

Pragmatic multicentre randomised controlled trial evaluating the impact of a routine molecular point-of-care ‘test-and-treat’ strategy for influenza in adults hospitalised with acute respiratory illness (FluPOC): trial protocol
por: Beard, Kate, et al.
Publicado: (2019)

Combined RT-PCR and Host Response Point-of-Care Testing in Patients Hospitalised with Suspected COVID-19: A Prospective Diagnostic Accuracy Study
por: Brendish, Nathan J., et al.
Publicado: (2022)

Clinical impact of molecular point-of-care testing for suspected COVID-19 in hospital (COV-19POC): a prospective, interventional, non-randomised, controlled study
por: Brendish, Nathan J, et al.
Publicado: (2020)

SARS-CoV-2 has displaced other seasonal respiratory viruses: Results from a prospective cohort study
por: Poole, Stephen, et al.
Publicado: (2020)

Influenza vaccination: protecting the most vulnerable
por: Tanner, Alex R., et al.
Publicado: (2021)

2796. The Impact of Syndromic Molecular Point-of-Care Testing for Respiratory Viruses on Antibiotic Use in Adults Presenting to Hospital with Exacerbation of Airways Disease: Further Analysis From a Randomized Controlled Trial
por: Clark, Tristan William, et al.
Publicado: (2019)

120. Impact of a Molecular Point-of-care ‘test and Treat’ Strategy for Influenza in Hospitalised adults: A Multi-centre, Randomised Controlled Trial (FluPOC)
por: Clark, Tristan William, et al.
Publicado: (2020)

Clinical impact of a routine, molecular, point-of-care, test-and-treat strategy for influenza in adults admitted to hospital (FluPOC): a multicentre, open-label, randomised controlled trial
por: Clark, Tristan W, et al.
Publicado: (2021)

Molecular point-of-care testing for respiratory viruses versus routine clinical care in adults with acute respiratory illness presenting to secondary care: a pragmatic randomised controlled trial protocol (ResPOC)
por: Brendish, Nathan J., et al.
Publicado: (2017)

A hyperinflammation clinical risk tool, HI5-NEWS2, stratifies hospitalised COVID-19 patients to associate risk of death and effect of early dexamethasone in an observational cohort
por: Ardern-Jones, Michael R., et al.
Publicado: (2023)

Point-of-care testing for respiratory viruses in adults: The current landscape and future potential
por: Brendish, Nathan J., et al.
Publicado: (2015)

Re: 'Syndromic panels or “panel syndrome”? A perspective through the lens of respiratory-tract infections' by Zanella et al
por: Brendish, N.J., et al.
Publicado: (2020)

415. Clinical Impact of Molecular Point-of-Care Testing for COVID-19 in Adults Presenting to Hospital: A Prospective, Interventional, Non-Randomised, Controlled Study
por: Brendish, Nathan J, et al.
Publicado: (2020)

Automated data cleaning of paediatric anthropometric data from longitudinal electronic health records: protocol and application to a large patient cohort
por: Phan, Hang T. T., et al.
Publicado: (2020)

Impact of point-of-care testing for respiratory viruses on antibiotic use in adults with exacerbation of airways disease
por: Brendish, Nathan J., et al.
Publicado: (2019)

Inflammatory phenotyping predicts clinical outcome in COVID-19
por: Burke, H., et al.
Publicado: (2020)

Diagnostic accuracy of the FebriDx host response point-of-care test in patients hospitalised with suspected COVID-19
por: Clark, Tristan W., et al.
Publicado: (2020)

Is Higher Viral Load in SARS-CoV-2 Associated with Death?
por: Faíco-Filho, Klinger Soares, et al.
Publicado: (2020)

Viral load at hospitalization is an independent predictor of severe COVID‐19
por: Waller, Hjalmar, et al.
Publicado: (2022)

Routine molecular point-of-care testing for respiratory viruses in adults presenting to hospital with acute respiratory illness (ResPOC): a pragmatic, open-label, randomised controlled trial
por: Brendish, Nathan J, et al.
Publicado: (2017)

Asthma did not increase in‐hospital COVID‐19‐related mortality in a tertiary UK hospital
por: Fong, Wei Chern Gavin, et al.
Publicado: (2021)

Viral load is strongly associated with length of stay in adults hospitalised with viral acute respiratory illness
por: Clark, Tristan W., et al.
Publicado: (2016)

SARS-CoV-2 viral load in nasopharyngeal swabs is not an independent predictor of unfavorable outcome
por: Salto-Alejandre, Sonsoles, et al.
Publicado: (2021)

SARS-COV-2 VIRAL LOAD AND CARDIAC INJURY ARE INDEPENDENT AND INCREMENTAL PREDICTORS OF IN-HOSPITAL MORTALITY
por: Chehab, Omar, et al.
Publicado: (2021)

SARS-CoV-2 Viral Load and Myocardial Injury: Independent and Incremental Predictors of Adverse Outcome
por: Chehab, Omar, et al.
Publicado: (2021)

HIV viral load assessment in multiple sanctuaries – case presentation
por: Streinu-Cercel, Anca, et al.
Publicado: (2014)

Evidence of a genetically driven metabolomic signature in actively inflamed Crohn’s disease
por: Mossotto, Enrico, et al.
Publicado: (2022)

Evaluation of Viral Loads in Patients With SARS-CoV-2 Delta Variant Infection: Higher Loads Do Not Translate Into Different Testing Scenarios
por: Gomez Marti, Juan Luis, et al.
Publicado: (2022)

PCR Test Positivity and Viral Loads during Three SARS-CoV-2 Viral Waves in Mumbai, India
por: Nikam, Chaitali, et al.
Publicado: (2023)

SARS-CoV-2 viral RNA levels are not 'viral load'
por: Michalakis, Yannis, et al.
Publicado: (2021)

Normalization of SARS-CoV-2 viral load via RT-qPCR provides higher-resolution data for comparison across time and between patients
por: Porter, W. Tanner, et al.
Publicado: (2021)

Development of multiplexed reverse-transcription loop-mediated isothermal amplification for detection of SARS-CoV-2 and influenza viral RNA
por: Zhang, Yinhua, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7oapcbrrl18gfnp01nsirven6b