A Case of Acquired von Willebrand Syndrome Complicated by Acute Myelomonocytic Leukemia

We here report a 21-year-old male who presented with acute myelomonocytic leukemia (AMML) associated with acquired von Willebrand syndrome (AVWS). To our knowledge, this is the first case of AVWS caused by AMML. In our case, following remission-induction chemotherapy combined with idarubicin and cyt...

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Detalles Bibliográficos
Autores principales: Fukatsu, Masahiko, Ohkawara, Hiroshi, Takahashi, Hiroshi, Mori, Hirotaka, Yaginuma, Mai, Endo, Mamiko, Shichishima-Nakamura, Akiko, Sano, Takahiro, Harada-Shirado, Kayo, Kimura, Satoshi, Ogawa, Kazuei, Hashimoto, Yuko, Ikezoe, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339464/
https://www.ncbi.nlm.nih.gov/pubmed/34413747
http://dx.doi.org/10.1159/000517439
Descripción
Sumario:We here report a 21-year-old male who presented with acute myelomonocytic leukemia (AMML) associated with acquired von Willebrand syndrome (AVWS). To our knowledge, this is the first case of AVWS caused by AMML. In our case, following remission-induction chemotherapy combined with idarubicin and cytarabine, the patient showed remarkable improvement of bleeding symptoms due to AVWS. Moreover, after an allogeneic stem cell transplantation from a sibling donor, both AMML and AVWS maintain complete remission.

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