Zinc attenuates ferroptosis and promotes functional recovery in contusion spinal cord injury by activating Nrf2/GPX4 defense pathway

AIM: Spinal cord injury (SCI) involves multiple pathological processes. Ferroptosis has been shown to play a critical role in the injury process. We wanted to explore whether zinc can inhibit ferroptosis, reduce inflammation, and then exert a neuroprotective effect. METHODS: The Alice method was use...

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Detalles Bibliográficos
Autores principales: Ge, Ming‐hao, Tian, He, Mao, Liang, Li, Dao‐yong, Lin, Jia‐quan, Hu, Heng‐shuo, Huang, Shuo‐cheng, Zhang, Chuan‐jie, Mei, Xi‐fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339532/
https://www.ncbi.nlm.nih.gov/pubmed/33951302
http://dx.doi.org/10.1111/cns.13657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339532/
https://www.ncbi.nlm.nih.gov/pubmed/33951302
http://dx.doi.org/10.1111/cns.13657

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