c-Src Increases the Sensitivity to TKIs in the EGFR-Mutant Lung Adenocarcinoma

c-Src and the epidermal growth factor receptor (EGFR) are key apical kinases that govern cell responses to microenvironmental cues. How c-Src affects EGFR-related signaling and targeted therapy remains elusive. Initially, caspase-8 phosphorylated at tyrosine 380 by c-Src predominantly enhancing c-Sr...

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Detalles Bibliográficos
Autores principales: Min, Weili, He, Chenyang, Zhang, Shuqun, Zhao, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339729/
https://www.ncbi.nlm.nih.gov/pubmed/34367939
http://dx.doi.org/10.3389/fonc.2021.602900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339729/
https://www.ncbi.nlm.nih.gov/pubmed/34367939
http://dx.doi.org/10.3389/fonc.2021.602900

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